Thiazole: A versatile standalone moiety contributing to the development of various drugs and biologically active agents
For many decades, the thiazole moiety has been an important heterocycle in the world of
chemistry. The thiazole ring consists of sulfur and nitrogen in such a fashion that the pi (π) …
chemistry. The thiazole ring consists of sulfur and nitrogen in such a fashion that the pi (π) …
Thiazoles, their benzofused systems, and thiazolidinone derivatives: versatile and promising tools to combat antibiotic resistance
S Cascioferro, B Parrino, D Carbone… - Journal of medicinal …, 2020 - ACS Publications
Thiazoles, their benzofused systems, and thiazolidinone derivatives are widely recognized
as nuclei of great value for obtaining molecules with various biological activities, including …
as nuclei of great value for obtaining molecules with various biological activities, including …
Theoretical investigations on the HOMO–LUMO gap and global reactivity descriptor studies, natural bond orbital, and nucleus-independent chemical shifts analyses of 3-phenylbenzo[d] …
M Miar, A Shiroudi, K Pourshamsian… - Journal of Chemical …, 2021 - journals.sagepub.com
Natural bond orbital analysis, salvation, and substituent effects of electron-releasing (–CH3,–
OH) and electron-withdrawing (–Cl,–NO2,–CF3) groups at para positions on the molecular …
OH) and electron-withdrawing (–Cl,–NO2,–CF3) groups at para positions on the molecular …
Thiazolidin-4-ones as potential antimicrobial agents: Experimental and in silico evaluation
Herein, we report computational and experimental evaluations of the antimicrobial activity of
twenty one 2, 3-diaryl-thiazolidin-4-ones. All synthesized compounds exhibited an …
twenty one 2, 3-diaryl-thiazolidin-4-ones. All synthesized compounds exhibited an …
Therapeutic advancement of benzothiazole derivatives in the last decennial period
S Tariq, P Kamboj, M Amir - Archiv der Pharmazie, 2019 - Wiley Online Library
Benzothiazole, a fused heterocyclic moiety, has attracted synthetic and medicinal chemists
for good reasons. It is a valuable scaffold that possesses diverse biological activities, such …
for good reasons. It is a valuable scaffold that possesses diverse biological activities, such …
New vinyl-1, 2, 4-triazole derivatives as antimicrobial agents: Synthesis, biological evaluation and molecular docking studies
E Stingaci, M Zveaghinteva, S Pogrebnoi… - Bioorganic & Medicinal …, 2020 - Elsevier
Triazole is a very important scaffold in medicinal chemistry due to the wide spectrum of
biological activities and mainly antifungal activity of 1, 2, 4-triazole derivatives. The main …
biological activities and mainly antifungal activity of 1, 2, 4-triazole derivatives. The main …
5-Adamantan thiadiazole-based thiazolidinones as antimicrobial agents. Design, synthesis, molecular docking and evaluation
M Fesatidou, P Zagaliotis, C Camoutsis… - Bioorganic & Medicinal …, 2018 - Elsevier
In continuation of our efforts to develop new compounds with antimicrobial properties we
describe design, synthesis, molecular docking study and evaluation of antimicrobial activity …
describe design, synthesis, molecular docking study and evaluation of antimicrobial activity …
Current perspective of synthesis of medicinally relevant benzothiazole based molecules: Potential for antimicrobial and anti-inflammatory activities
K Gupta, AK Sirbaiya, V Kumar… - Mini Reviews in …, 2022 - ingentaconnect.com
The therapeutic potential of the majority of the marketed drugs is due to the presence of a
heterocyclic nucleus, which constitutes a huge role in the field of medicinal chemistry. These …
heterocyclic nucleus, which constitutes a huge role in the field of medicinal chemistry. These …
Recent insights into antibacterial potential of benzothiazole derivatives
Antimicrobial resistance (AMR) is a worldwide concern among infectious diseases due to
increased mortality, morbidity and treatment cost. According to WHO 2019 report, among the …
increased mortality, morbidity and treatment cost. According to WHO 2019 report, among the …
Synthesis, in‐vitro and in‐silico study of novel thiazoles as potent antibacterial agents and MurB inhibitors
Efficient procedures are herein reported for the synthesis of novel hybrid thiazoles via a one‐
pot three‐component protocol. The protocol involves the reaction of novel aldehyde …
pot three‐component protocol. The protocol involves the reaction of novel aldehyde …