Current advance of nanotechnology in diagnosis and treatment for malignant tumors

B Wang, S Hu, Y Teng, J Chen, H Wang, Y Xu… - … and Targeted Therapy, 2024 - nature.com
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …

General insight into cancer: An overview of colorectal cancer

SM Alzahrani, HA Al Doghaither… - Molecular and …, 2021 - spandidos-publications.com
Cancer is currently among the leading causes of mortality globally. Colorectal cancer (CRC)
ranks second among the most common types of cancer in terms of mortality worldwide. This …

Pyroptosis in health and disease: mechanisms, regulation and clinical perspective

Y Liu, R Pan, Y Ouyang, W Gu, T Xiao… - Signal transduction and …, 2024 - nature.com
Pyroptosis is a type of programmed cell death characterized by cell swelling and osmotic
lysis, resulting in cytomembrane rupture and release of immunostimulatory components …

CCL19-producing fibroblasts promote tertiary lymphoid structure formation enhancing anti-tumor IgG response in colorectal cancer liver metastasis

Y Zhang, G Liu, Q Zeng, W Wu, K Lei, C Zhang, M Tang… - Cancer Cell, 2024 - cell.com
Tertiary lymphoid structures (TLSs) are associated with enhanced immunity in tumors.
However, their formation and functions in colorectal cancer liver metastasis (CRLM) remain …

Blocking the Wnt/β-catenin signaling pathway to treat colorectal cancer: Strategies to improve current therapies

Y Chen, M Chen, K Deng - International journal of …, 2022 - spandidos-publications.com
Colorectal cancer (CRC) is one of the most common malignant tumor types occurring in the
digestive system. The incidence of CRC has exhibits yearly increases and the mortality rate …

Tertiary lymphoid structures in diseases: immune mechanisms and therapeutic advances

L Zhao, S Jin, S Wang, Z Zhang, X Wang… - … and Targeted Therapy, 2024 - nature.com
Tertiary lymphoid structures (TLSs) are defined as lymphoid aggregates formed in non-
hematopoietic organs under pathological conditions. Similar to secondary lymphoid organs …

The Physiology of Enteric Glia

J Gonzales, BD Gulbransen - Annual Review of Physiology, 2024 - annualreviews.org
Enteric glia are the partners of neurons in the enteric nervous system throughout the
gastrointestinal tract. Roles fulfilled by enteric glia are diverse and contribute to maintaining …

LncRNA-encoded peptides in cancer

Y Zhang - Journal of Hematology & Oncology, 2024 - Springer
Long non-coding RNAs (lncRNAs), once considered transcriptional noise, have emerged as
critical regulators of gene expression and key players in cancer biology. Recent …

Polyclonal-to-monoclonal transition in colorectal precancerous evolution

Z Lu, S Mo, D Xie, X Zhai, S Deng, K Zhou, K Wang… - Nature, 2024 - nature.com
Unravelling the origin and evolution of precancerous lesions is crucial for effectively
preventing malignant transformation, yet our current knowledge remains limited 1, 2, 3. Here …

Targeting circ-0034880-enriched tumor extracellular vesicles to impede SPP1highCD206+ pro-tumor macrophages mediated pre-metastatic niche formation in …

J Zhou, Q Song, H Li, Y Han, Y Pu, L Li, W Rong, X Liu… - Molecular Cancer, 2024 - Springer
Background Information transmission between primary tumor cells and immunocytes or
stromal cells in distal organs is a critical factor in the formation of pre-metastatic niche …