Normal skeletal muscle functions are affected following trauma, chronic diseases, inherited
neuromuscular disorders, aging, and cachexia, hampering the daily activities and quality of …

Skeletal muscle is highly irrigated by blood vessels. Beyond oxygen and nutrient supply,
new vessel functions have been identified. This review presents vessel microanatomy and …

In skeletal muscle, new functions for vessels have recently emerged beyond oxygen and
nutrient supply, through the interactions that vascular cells establish with muscle stem cells …

Autoimmune myopathies (myositides) are strongly associated with malignancy. The link
between myositis and cancer, originally noticed by Bohan and Peter in their classification in …

The satellite cells, which serve as adult muscle stem cells, are both located beneath
myofiber basement membranes and closely associated with capillary endothelial cells. We …

Different mechanisms have been proposed to explain the pathological basis of
perifascicular muscle fibre atrophy in dermatomyositis. These include ischaemia due to …

Studies confirm IFN, particularly type I and II IFN, is an important part of JDM pathogenesis
by the level of dysregulation and correlation with disease activity, as well as IFN …

The anti-melanoma differentiation-associated gene 5 (MDA5) autoantibody is specifically
associated with dermatomyositis (DM). Nevertheless, anti–MDA5+-patients experience …

Dermatomyositis (DM) is an autoimmune disease associated with enhanced type I interferon
(IFN) signalling in skeletal muscle, but the mechanisms underlying muscle dysfunction and …

Amyopathic dermatomyositis can be a challenging diagnosis because patients lack
traditional muscle findings.“Clinically amyopathic” dermatomyositis (CADM) accounts for the …