Telomeres, the ends of linear eukaryotic chromosomes, are characterized by the presence
of multiple repeats of a short DNA sequence. This telomeric DNA is protected from illicit …

Telomerase is the essential reverse transcriptase required for linear chromosome
maintenance in most eukaryotes. Telomerase supplements the tandem array of simple …

Telomerase adds telomeric repeats at chromosome ends to compensate for the telomere
loss that is caused by incomplete genome end replication. In humans, telomerase is …

Telomerase is a special reverse transcriptase ribonucleoprotein dedicated to the synthesis
of telomere repeats that protect chromosome ends. Among reverse transcriptases …

The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

Mutations in the essential telomerase genes TERT and TR cause familial pulmonary fibrosis;
however, in telomerase-null mice, short telomeres predispose to emphysema after chronic …

Telomerase adds simple-sequence repeats to the ends of linear chromosomes to counteract
the loss of end sequence inherent in conventional DNA replication. Catalytic activity for …

INTRODUCTION Telomerase is a ribonucleoprotein complex that extends the telomere DNA
at the 3′ ends of linear chromosomes, thereby counteracting the loss of DNA from …

Telomerase is a reverse transcriptase specialized in the addition of telomeric DNA repeats
onto the ends of chromosomes. Telomere extension offsets the loss of telomeric repeats …

Telomerase is the eukaryotic solution to the 'end-replication problem'of linear chromosomes
by synthesising the highly repetitive DNA constituent of telomeres, the nucleoprotein cap …