4004 ESC Guidelines label use of medication should be limited to situations where it is in
the patient's interest to do so, with regard to the quality, safety, and efficacy of care, and only …

Abstract Aim The “2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure”
replaces the “2013 ACCF/AHA Guideline for the Management of Heart Failure” and the …

Heart Failure (HF) is a multi-faceted and life-threatening syndrome characterized by
significant morbidity and mortality, poor functional capacity and quality of life, and high costs …

Importance Acute myocarditis, defined as a sudden inflammatory injury to the myocardium,
affects approximately 4 to 14 people per 100 000 each year globally and is associated with …

Transforming growth factor-β (TGFβ) isoforms are upregulated and activated in myocardial
diseases and have an important role in cardiac repair and remodelling, regulating the …

Trypanosoma cruzi is the etiological agent of Chagas disease, usually transmitted by
triatomine vectors. An estimated 20 to 30% of infected individuals develop potentially lethal …

Abstract We combined American Community Survey data with age-specific Trypanosoma
cruzi prevalence derived from US surveys and World Health Organization reports to yield …

In view of the increasing complexity of both cardiovascular implantable electronic devices
(CIEDs) and patients in the current era, practice guidelines, by necessity, have become …

Heart failure (HF) is a heterogeneous clinical syndrome marked by substantial morbidity and
mortality. The natural history of HF is well established; however, epidemiological data are …

Chagas disease (CD), also known as American trypanosomiasis, is a multisystemic disorder
that can affect the cardiovascular, digestive, and central nervous systems. 1 CD is caused by …