Risk estimation for the primary prevention of cardiovascular disease: considerations for appropriate risk prediction model selection

KR van Daalen, D Zhang, S Kaptoge… - The Lancet Global …, 2024 - thelancet.com
Cardiovascular diseases remain the number one cause of death globally. Cardiovascular
disease risk scores are an integral tool in primary prevention, being used to identify …

Prognosticating the outcome of intensive care in older patients—a narrative review

M Beil, R Moreno, J Fronczek, Y Kogan… - Annals of Intensive …, 2024 - Springer
Prognosis determines major decisions regarding treatment for critically ill patients. Statistical
models have been developed to predict the probability of survival and other outcomes of …

Robust and consistent biomarker candidates identification by a machine learning approach applied to pancreatic ductal adenocarcinoma metastasis

T Mahawan, T Luckett, A Mielgo Iza… - BMC Medical Informatics …, 2024 - Springer
Abstract Background Machine Learning (ML) plays a crucial role in biomedical research.
Nevertheless, it still has limitations in data integration and irreproducibility. To address these …

Evaluation of Predictive Reliability to Foster Trust in Artificial Intelligence. A case study in Multiple Sclerosis

L Peracchio, G Nicora, E Parimbelli… - arXiv preprint arXiv …, 2024 - arxiv.org
Applying Artificial Intelligence (AI) and Machine Learning (ML) in critical contexts, such as
medicine, requires the implementation of safety measures to reduce risks of harm in case of …

Bayesian Networks in the Management of Hospital Admissions: A Comparison between Explainable AI and Black Box AI during the Pandemic

G Nicora, M Catalano, C Bortolotto, MF Achilli… - Journal of …, 2024 - mdpi.com
Artificial Intelligence (AI) and Machine Learning (ML) approaches that could learn from large
data sources have been identified as useful tools to support clinicians in their decisional …

Sample size for developing a prediction model with a binary outcome: targeting precise individual risk estimates to improve clinical decisions and fairness

RD Riley, GS Collins, R Whittle, L Archer… - arXiv preprint arXiv …, 2024 - arxiv.org
When developing a clinical prediction model, the sample size of the development dataset is
a key consideration. Small sample sizes lead to greater concerns of overfitting, instability …

Speculations on Uncertainty and Humane Algorithms

N Gray - arXiv preprint arXiv:2408.06736, 2024 - arxiv.org
The appreciation and utilisation of risk and uncertainty can play a key role in helping to solve
some of the many ethical issues that are posed by AI. Understanding the uncertainties can …

Development and validation of a novel clinical risk score to predict hypoxemia in children with pneumonia using the WHO PREPARE dataset

R Tan, A Chandna, T Colbourn, S Hooli, C King… - medRxiv, 2024 - medrxiv.org
Background Hypoxemia predicts mortality at all levels of care, and appropriate management
can reduce preventable deaths. However, pulse oximetry and oxygen therapy remain …

Development and Validation of a Diagnostic Prediction Rule for Osteopenia

T Janwittayanuchit, N Kaewboonlert… - medRxiv, 2024 - medrxiv.org
Objectives To triage patients with a high likelihood of osteopenia before referring them for a
standard bone mass density test for diagnosis. Introduction Osteopenia defined by low bone …

Bedside variables to guide decision-making in critically ill patients

E Cox - 2024 - research.rug.nl
Patients admitted to the intensive care unit (ICU) suffer from various diseases and
comorbidities. Only critically ill patients that require continuous care, organ support, or …