Anthropogenic contaminants of high concern: Existence in water resources and their adverse effects

IY López-Pacheco, A Silva-Núñez… - Science of the Total …, 2019 - Elsevier
Existence of anthropogenic contaminants (ACs) in different environmental matrices is a
serious and unresolved concern. For instance, ACs from different sectors, such as industrial …

[HTML][HTML] Sphingolipids as prognostic biomarkers of neurodegeneration, neuroinflammation, and psychiatric diseases and their emerging role in lipidomic investigation …

D van Kruining, Q Luo, G van Echten-Deckert… - Advanced drug delivery …, 2020 - Elsevier
Lipids play an important role in neurodegeneration, neuroinflammation, and psychiatric
disorders and an imbalance in sphingolipid levels is associated with disease. Although early …

Airborne fine particulate matter induces cognitive and emotional disorders in offspring mice exposed during pregnancy

C Zhao, P Xie, T Yong, W Huang, J Liu, D Wu, F Ji, M Li… - Science Bulletin, 2021 - Elsevier
Gestational exposure to PM 2.5 is associated with adverse postnatal outcomes. PM 2.5 can
enter alveoli by using intratracheal instillation, even penetrate through lung cells into the …

Mass spectrometry-based phospholipid imaging: methods and findings

A Mamun, A Islam, F Eto, T Sato, T Kahyo… - Expert review of …, 2020 - Taylor & Francis
Introduction: Imaging is a technique used for direct visualization of the internal structure or
distribution of biomolecules of a living system in a two-dimensional or three-dimensional …

Caveolin-1 regulates medium spiny neuron structural and functional plasticity

KRT Eisinger, AD Chapp, SP Swanson, D Tam… - …, 2020 - Springer
Abstract Rationale Caveolin-1 (CAV1) is a structural protein critical for spatial organization of
neuronal signaling molecules. Whether CAV1 is required for long-lasting neuronal plasticity …

Untargeted lipidomic analysis of human hippocampus for temporal lobe epilepsy with hippocampal sclerosis

H Zhang, P Ren, Y Huang, W Zeng, K Zhong, H Gao… - Epilepsy Research, 2020 - Elsevier
Mesial temporal lobe epilepsy (mTLE), a very common chronic neurological disorder, is
frequently accompanied by neurodegeneration in the hippocampus, resulting in …

[HTML][HTML] Postruminal choline supply during negative nutrient balance alters components of hepatic mTOR signaling and plasma amino acids in lactating Holstein cows

DN Sherlock, E Abdel-Hamied, R Bucktrout… - Journal of Dairy …, 2023 - Elsevier
Choline requirements for dairy cattle are unknown. However, enhanced postruminal supply
of choline may increase flux through the methionine cycle to spare Met for other functions …

Location and Cell-Type-Specific Bias of Metabotropic Glutamate Receptor, mGlu5, Negative Allosteric Modulators

YJI Jong, SK Harmon, KL O'Malley - ACS chemical neuroscience, 2019 - ACS Publications
Emerging data indicate that G-protein coupled receptor (GPCR) signaling is determined by
not only the agonist and a given receptor but also a variety of cell-type-specific factors that …

mTOR regulates cocaine-induced behavioural sensitization through the SynDIG1–GluA2 interaction in the nucleus accumbens

H Li, J Zhang, R Xu, Y Wang, W Xu, R Chen… - Acta Pharmacologica …, 2022 - nature.com
Behavioral sensitization is a progressive increase in locomotor or stereotypic behaviours in
response to drugs. It is believed to contribute to the reinforcing properties of drugs and to …

Repeated low-dose exposures to sarin disrupted the homeostasis of phospholipid and sphingolipid metabolism in guinea pig hippocampus

M Shi, S Deng, Y Cui, X Chen, T Shi, L Song, R Zhang… - Toxicology Letters, 2021 - Elsevier
Repeated low-level exposure to sarin results to hippocampus dysfunction. Metabonomics
involves a holistic analysis of a set of metabolites in an organism in the search for a …