Biotransformations already represent an effective and sometimes preferable alternative to
chemical synthesis for the production of fine chemicals and optically active compounds. To …

The synthesis of the amide bond between an amine and a carboxylic acid is one of the most
significant reactions in industrial pharmaceutical synthesis. Despite the apparent simplicity …

From reviews to the first edtion:" Bornscheuer and Kazlauskas have set out, and succeeded,
in producing a definitive manual on hydrolytic enzymes (especially lipases, esterases, and …

The application of the B-component lipase from the yeast Candida antarctica in organic
synthesis is reviewed. This enzyme has been found to be a particularly efficient and robust …

Amide bond-containing (ABC) biomolecules are some of the most intriguing and functionally
significant natural products with unmatched utility in medicine, agriculture and …

Biocatalysis in nonaqueous media is becoming increasingly important in organic synthesis.
Lipases are the most used enzymes, especially in transesterification reactions. However, in …

Enantiopure amines are used in the fine-chemicals industry as resolving agents, chiral
auxiliaries and chiral synthetic building blocks for pharmaceuticals and agrochemicals …

The lipase-catalyzed aminolysis of carboxylic esters is a fairly general reaction that has
been performed with a wide range of esters and amines, generally in anhydrous organic …

Abstract Bei der Fettverdauung im Magen und im Darm hydrolysieren sie Triacylglycerine,
aber auch außerhalb ihres angestammten Wirkungsbereichs können Lipasen zur Hydrolyse …

Lipases favor one enantiomer of secondary alcohols (HOCHRR′) and isosteric primary
amines (NH2CHRR′) while subtilisin favors the other enantiomer. In both cases, simple …