[HTML][HTML] Phytochemistry and pharmacological activity of the genus artemisia

D Bisht, D Kumar, D Kumar, K Dua… - Archives of Pharmacal …, 2021 - Springer
Artemisia and its allied species have been employed for conventional medicine in the
Northern temperate regions of North America, Europe, and Asia for the treatments of …

Bioinspired drug delivery strategies for repurposing conventional antibiotics against intracellular infections

S Subramaniam, P Joyce, N Thomas… - Advanced Drug Delivery …, 2021 - Elsevier
Bacteria have developed a wealth of strategies to avoid and resist the action of antibiotics,
one of which involves pathogens invading and forming reservoirs within host cells. Due to …

Host defense against Pseudomonas aeruginosa requires ceramide-rich membrane rafts

H Grassme, V Jendrossek, A Riehle, G Von Kürthy… - Nature medicine, 2003 - nature.com
Pseudomonas aeruginosa infection is a serious complication in patients with cystic fibrosis
and in immunocompromised individuals. Here we show that P. aeruginosa infection triggers …

[HTML][HTML] Ceramide-rich platforms in transmembrane signaling

B Stancevic, R Kolesnick - FEBS letters, 2010 - Elsevier
Recent evidence suggests that ceramide regulates stress signaling via reorganization of the
plasma membrane. The focus of this review will be to discuss the mechanism by which acid …

[HTML][HTML] Pseudomonas aeruginosa Pili and Flagella Mediate Distinct Binding and Signaling Events at the Apical and Basolateral Surface of Airway Epithelium

I Bucior, JF Pielage, JN Engel - PLoS pathogens, 2012 - journals.plos.org
Pseudomonas aeruginosa, an important opportunistic pathogen of man, exploits numerous
factors for initial attachment to the host, an event required to establish bacterial infection. In …

Pseudomonas aeruginosa lipopolysaccharide: a major virulence factor, initiator of inflammation and target for effective immunity

GB Pier - International journal of medical microbiology, 2007 - Elsevier
Pseudomonas aeruginosa is one of the most important bacterial pathogens encountered by
immunocompromised hosts and patients with cystic fibrosis (CF), and the lipopolysaccharide …

Vitronectin in bacterial pathogenesis: a host protein used in complement escape and cellular invasion

B Singh, YC Su, K Riesbeck - Molecular microbiology, 2010 - Wiley Online Library
The multifunctional human glycoprotein vitronectin (Vn) plays a significant role in cell
migration, tissue repair and regulation of membrane attack complex (MAC) formation. It also …

CFTR is a pattern recognition molecule that extracts Pseudomonas aeruginosa LPS from the outer membrane into epithelial cells and activates NF-κB translocation

TH Schroeder, MM Lee, PW Yacono… - Proceedings of the …, 2002 - National Acad Sciences
Immune cells are activated during cellular responses to antigen by two described
mechanisms:(i) direct uptake of antigen and (ii) extraction and internalization of membrane …

The pathogenesis of bacterial keratitis: studies with Pseudomonas aeruginosa

SMJ Fleiszig, DJ Evans - Clinical and Experimental Optometry, 2002 - Wiley Online Library
Bacterial keratitis is a sight‐threatening corneal disease that is most commonly associated
with the extended wear of soft contact lenses. Over the past decade, we have investigated …

The Phosphoinositol-3-Kinase–Protein Kinase B/Akt Pathway Is Critical for Pseudomonas aeruginosa Strain PAK Internalization

A Kierbel, A Gassama-Diagne, K Mostov… - Molecular biology of …, 2005 - Am Soc Cell Biol
Several Pseudomonas aeruginosa strains are internalized by epithelial cells in vitro and in
vivo, but the host pathways usurped by the bacteria to enter nonphagocytic cells are not …