Inflammatory and non-invasive vascular markers: the multimarker approach for risk stratification in coronary artery disease

I Ikonomidis, K Stamatelopoulos, J Lekakis… - Atherosclerosis, 2008 - Elsevier
Current thinking supports the notion that several inflammatory proteins intervene with
endothelium and haemostatic factors leading to plaque formation and rupture. Of these, C …

Mechanisms of non-opioid analgesics beyond cyclooxygenase enzyme inhibition

M Hamza, RA Dionne - Current molecular pharmacology, 2009 - ingentaconnect.com
Non-opioid analgesics including both selective and non-selective cyclooxygenase (COX)
inhibitors and acetaminophen are the most widely used treatments for pain. Inhibition of …

Effect of colchicine (0.5 mg twice daily) on high-sensitivity C-reactive protein independent of aspirin and atorvastatin in patients with stable coronary artery disease

M Nidorf, PL Thompson - The American journal of cardiology, 2007 - Elsevier
In patients with stable coronary artery disease, elevated levels of biomarkers of
inflammation, including high-sensitivity C-reactive protein (hs-CRP)≥ 2.0 mg/L, are …

COX‐1 and vascular disease

PM Vanhoutte - Clinical Pharmacology & Therapeutics, 2009 - Wiley Online Library
Since the discovery of the pivotal role of cyclooxygenase (COX) in the metabolism of
arachidonic acid, vascular biologists have been confronted with the duality of this system …

[PDF][PDF] Interaction between selective cyclooxygenase inhibitors and capsaicin-sensitive afferent sensory nerves in pathogenesis of stress-induced gastric lesions. Role …

S Kwiecien, PC Konturek, Z Sliwowski… - Journal of Physiology …, 2012 - jpp.krakow.pl
Gastric microcirculation plays an important role in the maintenance of the mucosal gastric
integrity and the mechanism of injury as well as providing protection to the gastric mucosa …

Nitric oxide and cardiovascular effects: new insights in the role of nitric oxide for the management of osteoarthritis

IS Mackenzie, D Rutherford, TM MacDonald - Arthritis research & therapy, 2008 - Springer
Nitric oxide (NO) is an important mediator in both health and disease. In addition to its effects
on vascular tone and platelet function, it plays roles in inflammation and pain perception that …

Melanoma inhibition by cyclooxygenase inhibitors: role of interleukin-6 suppression, a putative mechanism of action, and clinical implications

RE Kast - Medical Oncology, 2007 - Springer
Melanoma progression is often associated with supranormal levels of interleukin-6 (IL-6). Il-
6 is an important growth factor for many cases of melanoma. A recent case report by …

[PDF][PDF] The influence of thrombolytic therapy on C-reactive protein in ST-segment elevation acute myocardial infarction

AK Tsakiris, PG Marnelos, NS Nearchou… - Hellenic J …, 2006 - hellenicjcardiol.org
Background: Inflammation plays a crucial role in atherosclerotic processes and in acute
coronary syndromes (ACS). Strong evidence of this is the elevation of C-reactive protein …

Effects of short-term anti-inflammatory therapy on endothelial function in patients with non-ST-segment elevation acute coronary syndrome

M Chyrchel, D Dudek, Ł Rzeszutko, A Dziewierz… - Cardiovascular …, 2011 - Elsevier
The aim was to assess the impact of the short-term anti-inflammatory therapy on coronary
endothelial function in non-ST-segment elevation acute coronary syndrome patients. In 30 …

Identifying the Role of Flow-Mediated Dilatation Assessment in Acute Coronary Syndromes: A Systematic Review

G Zormpas, A Boulmpou, V Potoupni, F Siskos… - Cardiology in … - journals.lww.com
In the context of the global burden of cardiovascular disease, the development of novel,
patient-targeted diagnostic and therapeutic strategies is of paramount importance. Acute …