Managing efficacy and toxicity of drugs: Targeted delivery and excretion

P Kundu, S Das, N Chattopadhyay - International Journal of Pharmaceutics, 2019 - Elsevier
Medicine is a natural companion of mankind in the present era for mere survival from the
deadly diseases in ever-increasing polluted environments. Hence, in recent years, major …

Host-guest complexation of eugenol in cyclodextrins for enhancing bioavailability

A Joardar, G Meher, BP Bag, H Chakraborty - Journal of Molecular Liquids, 2020 - Elsevier
Eugenol is known for its beneficial health effects. However, its low bioavailability requires
administration of higher doses to achieve the desired effect. Host-guest complexation is …

Idarubicin/mithramycin-acridine orange combination drugs co-loaded by DNA nanostructures: Different effects of intercalation and groove binding on drug release and …

D Wang, M Liu, Y Wu, T Weng, L Wang, Y Zhang… - Journal of Molecular …, 2022 - Elsevier
The co-loading of chemotherapy-phototherapy (CTPT) combination drugs by aptamer-
targeted DNA nanostructures has significant advantages in improving anticancer effects and …

Cavity size dependent stoichiometry of probe–cyclodextrin complexation: Experimental and molecular docking demonstration

S Das, S Nath, TS Singh, N Chattopadhyay - Journal of Photochemistry and …, 2020 - Elsevier
Host-guest interaction of a newly synthesized intramolecular charge transfer (ICT) probe,
namely (E)-4-(4-(diethylamino) benzylideneamino)-2-(trifluoromethyl) benzonitrile (DBTFB) …

A fluorescence approach on the investigation of urea derivatives interaction with a non-PET based acridinedione dye-beta Cyclodextrin (β-CD) complex in water …

A Krishnan, T Viruthachalam, K Rajendran - Spectrochimica Acta Part A …, 2021 - Elsevier
Photophysical studies of resorcinol based acridinedione dyes with beta Cyclodextrin (β-CD)
in the presence of urea (U) and tetramethylurea (TMU) were carried out in water. A marked …

Endogenous activation-induced delivery of a bioactive photosensitizer from a micellar carrier to natural DNA

M Afzal, S Ghosh, S Das… - The Journal of Physical …, 2016 - ACS Publications
The photophysics of phenosafranin (PSF), a member of the photosensitizer phenazinium
family, has been explored in nonionic Triton X-165 (TX-165) micelle, calf thymus DNA …

Origin of unusually high fluorescence anisotropy of 3-hydroxyflavone in water: Formation of probe–solvent cage-like cluster

S Das, S Chakrabarty… - The Journal of Physical …, 2019 - ACS Publications
Based on the unusually high fluorescence anisotropy (FA) of 3-hydroxyflavone (3HF) in
water medium in contrast to the very low FA of its methoxy counterpart (3MF), our proposition …

Dehydrogenation induced inhibition of intramolecular charge transfer in substituted pyrazoline analogues

P Kundu, D Banerjee, G Maiti… - Physical Chemistry …, 2017 - pubs.rsc.org
The detailed photophysics of (E)-1, 5-diphenyl-3-styryl-4, 5-dihydro-1H-pyrazole (DSDP)
and (E)-1, 5-diphenyl-3-styryl-1H-pyrazole (DSP) has been investigated and compared to …

Liposome‐Based Delivery of a Bis‐benzimidazole Derivative to Duplex DNA: A Spectroscopic Study

D Shit, P Mandal, P Das, S Pramanik - ChemistrySelect, 2024 - Wiley Online Library
Due to the immense pharmacological significance, the interaction of small molecules with
liposome and the exact knowledge of their binding location and distribution within the lipid …

Heteroatom controlled probe-water cluster formation of a series of ESIPT probes: An exploration with fluorescence anisotropy

S Das, N Chattopadhyay - Chemical Physics Letters, 2018 - Elsevier
The present letter reports unusual high fluorescence anisotropy of excited state
intramolecular proton transfer (ESIPT) prone 2-(2′-hydroxyphenyl) benzoxazole (HBO) in …