Over the past 10 years, major progress has been made in the pathogenesis of uric acid and
calcium stones. These advances have led to our further understanding of a pathogenetic link …

Oxalate degrading enzymes have a number of potential applications, including medical
diagnosis and treatments for hyperoxaluria and other oxalate-related diseases, the …

Metabolic engineering often entails concurrent engineering of substrate utilization, central
metabolism and product synthesis pathways, inevitably creating interdependency with …

The phototrophic bacterium Chloroflexus aurantiacus uses a yet unsolved 3-
hydroxypropionate cycle for autotrophic CO2 fixation. It starts from acetyl-CoA, with acetyl …

The human bile acid pool composition is composed of both primary bile acids (cholic acid
and chenodeoxycholic acid) and secondary bile acids (deoxycholic acid and lithocholic …

α-Methylacyl-CoA racemase (AMACR; P504S) catalyzes a key chiral inversion step in the
metabolism of branched-chain fatty acids, ibuprofen and related drugs. Protein levels are …

Aims: This study was undertaken to evaluate the oxalate‐degrading activity in several
Lactobacillus species widely used in probiotic dairy and pharmaceutical preparations …

Branched‐chain lipids are important components of the human diet and are used as drug
molecules, eg ibuprofen. Owing to the presence of methyl groups on their carbon chains …

Bile salts are natural detergents that facilitate the digestion and absorption of the
hydrophobic components of the diet. However, their amphiphilic nature makes them very …

Abstract The Powder River Basin (PRB) in southeastern Montana and northeastern
Wyoming contains massive coal deposits with biologically generated coal bed methane …