Hypercholesterolemia is a strong determinant of mortality and morbidity associated with
cardiovascular diseases and a major contributor to the global disease burden. Mutations in …

Background Studies have suggested that high-density lipoprotein (HDL) stimulates
scavenger receptor class B type 1 (SR-B1) to promote hepatic uptake of cholesterol. SR-B1 …

Background and aims Our study aimed to investigate the association between high-density
lipoprotein cholesterol (HDL-C) and all-cause and cause-specific mortality in Korean adults …

Background Several single nucleotide polymorphisms (SNPs) in lipid transport genes have
been shown to be associated with premature coronary artery disease (PCAD). The …

Background The present study was to detect the association of single nucleotide
polymorphism (SNP) in the breast susceptibility gene 2 (BRCA2) and the risk of coronary …

The SCARB1 gene encodes human scavenger receptor class B type I (SR-BI), the primary
receptor for high-density lipoprotein (HDL)-cholesteryl ester uptake, and polymorphisms in …

Recent genome-wide association studies (GWAS) have identified genetic variants
associated with coronary artery disease (CAD), ischemic stroke (IS) and serum lipid traits in …

Little is known about the association of the TIMD4 (T-cell immunoglobulin and mucin domain
4 gene)-HAVCR1 (hepatitis A virus cellular receptor 1) variants and lipid metabolism, the …

Background Hepatocyte nuclear factor‐1α gene (HNF1A) single nucleotide polymorphisms
(SNPs) have been associated with serum lipid traits in several previous genome‐wide …

Little is known about the association of the FADS1/FADS2 SNPs and serum lipid levels and
the risk of coronary artery disease (CAD) and ischemic stroke (IS) in the Chinese southern …