CaeNDR, the Caenorhabditis Natural Diversity Resource

TA Crombie, R McKeown, ND Moya… - Nucleic Acids …, 2024 - academic.oup.com
Studies of model organisms have provided important insights into how natural genetic
differences shape trait variation. These discoveries are driven by the growing availability of …

Screening of the Pandemic Response Box identifies anti-microsporidia compounds

Q Huang, J Chen, G Pan… - PLoS Neglected Tropical …, 2023 - journals.plos.org
Microsporidia are fungal obligate intracellular pathogens, which infect most animals and
cause microsporidiosis. Despite the serious threat that microsporidia pose to humans and …

[HTML][HTML] Getting around the roundworms: Identifying knowledge gaps and research priorities for the ascarids

AJ Wolstenholme, EC Andersen… - Advances in …, 2024 - ncbi.nlm.nih.gov
The ascarids are a large group of parasitic nematodes that infect a wide range of animal
species. In humans, they cause neglected diseases of poverty; many animal parasites also …

Quantifying the fitness effects of resistance alleles with and without anthelmintic selection pressure using Caenorhabditis elegans

AO Shaver, IR Miller, ES Schaye, ND Moya… - Plos …, 2024 - journals.plos.org
Albendazole (a benzimidazole) and ivermectin (a macrocyclic lactone) are the two most
commonly co-administered anthelmintic drugs in mass-drug administration programs …

Efficacy assessment of miltefosine and curcumin against Clonorchis sinensis infection

SO Lee, KB Chu, KW Yoon, GD Eom… - Antimicrobial agents …, 2024 - journals.asm.org
Praziquantel (PZQ) is currently the only approved drug for treating clonorchiasis, but its poor
efficacy against Clonorchis sinensis larvae has highlighted the need to develop newer …

[HTML][HTML] Quantitative tests of albendazole resistance in Caenorhabditis elegans beta-tubulin mutants

JB Collins, SA Stone, EJ Koury, AG Paredes… - International Journal for …, 2024 - Elsevier
Benzimidazole (BZ) anthelmintics are among the most important treatments for parasitic
nematode infections in the developing world. Widespread BZ resistance in veterinary …

[图书][B] Advances in parasitology

D Rollinson, SI Hay - 2012 - books.google.com
First published in 1963, Advances in Parasitology contains comprehensive and up-to-date
reviews in all areas of interest in contemporary parasitology. Advances in Parasitology …

Mapping resistance-associated anthelmintic interactions in the model nematode Caenorhabditis elegans

EG Rehborg, NJ Wheeler… - PLOS Neglected Tropical …, 2023 - journals.plos.org
Parasitic nematodes infect billions of people and are mainly controlled by anthelmintic mass
drug administration (MDA). While there are growing efforts to better understand mechanisms …

Praziquantel inhibits Caenorhabditis elegans development and species-wide differences might be cct-8-dependent

J Wit, CM Dilks, G Zhang, KSK Guisbert, S Zdraljevic… - Plos one, 2023 - journals.plos.org
Anthelmintic drugs are used to treat parasitic roundworm and flatworm infections in humans
and other animals. Caenorhabditis elegans is an established model to investigate …

[HTML][HTML] Quantitative tests of albendazole resistance in beta-tubulin mutants

JB Collins, SA Stone, EJ Koury, AG Paredes, F Shao… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Benzimidazole (BZ) anthelmintics are among the most important treatments for parasitic
nematode infections in the developing world. Widespread BZ resistance in veterinary …