Roles of clock genes in the pathogenesis of Parkinson's disease

AD Shkodina, SC Tan, MM Hasan… - Ageing Research …, 2022 - Elsevier
Parkinson's disease (PD) is a common motor disorder that has become increasingly
prevalent in the ageing population. Recent works have suggested that circadian rhythms …

MicroRNAs as potential orchestrators of Alzheimer's disease-related pathologies: insights on current status and future possibilities

NZ Abuelezz, FE Nasr, MA AbdulKader… - Frontiers in Aging …, 2021 - frontiersin.org
Alzheimer's disease (AD) is a progressive and deleterious neurodegenerative disease,
strongly affecting the cognitive functions and memory of seniors worldwide. Around 58% of …

The circadian clock component BMAL1 regulates SARS-CoV-2 entry and replication in lung epithelial cells

X Zhuang, S Tsukuda, F Wrensch, PAC Wing… - IScience, 2021 - cell.com
The coronavirus disease 2019 pandemic, caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) coronavirus, is a global health issue with unprecedented …

Sleep and memory: The impact of sleep deprivation on transcription, translational control, and protein synthesis in the brain

LC Lyons, Y Vanrobaeys, T Abel - Journal of neurochemistry, 2023 - Wiley Online Library
In countries around the world, sleep deprivation represents a widespread problem affecting
school‐age children, teenagers, and adults. Acute sleep deprivation and more chronic sleep …

Therapeutic potential of exosomes/miRNAs in polycystic ovary syndrome induced by the alteration of circadian rhythms

W Chen, Q Huang, Z Wang, X Zhuang, S Lin… - Frontiers in …, 2022 - frontiersin.org
Polycystic ovary syndrome (PCOS) is a reproductive dysfunction associated with endocrine
disorders and is most common in women of reproductive age. Clinical and/or biochemical …

2.4 GHz electromagnetic field influences the response of the circadian oscillator in the colorectal cancer cell line DLD1 to miR-34a-mediated regulation

S Olejárová, R Moravčík, I Herichová - International Journal of Molecular …, 2022 - mdpi.com
Radiofrequency electromagnetic fields (RF-EMF) exert pleiotropic effects on biological
processes including circadian rhythms. miR-34a is a small non-coding RNA whose …

The role of microRNAs in the molecular link between circadian rhythm and autism spectrum disorder

JY Kim, W Kim, KH Lee - Animal Cells and Systems, 2023 - Taylor & Francis
Circadian rhythm regulates physiological cycles of awareness and sleepiness. Melatonin
production is primarily regulated by circadian regulation of gene expression and is involved …

Tetrahedral DNA nanostructures enhance transcription isothermal amplification for multiplex detection of non-coding RNAs

ES Lee, J Woo, J Shin, BS Cha, S Kim… - Biosensors and …, 2024 - Elsevier
This study introduces an innovative detection system for multiple cancer biomarkers,
employing transcription isothermal amplification methods in conjunction with a tetrahedral …

Post-transcriptional modulators and mediators of the circadian clock

G Anna, NN Kannan - Chronobiology international, 2021 - Taylor & Francis
The endogenous circadian timekeeping system drives~ 24-h rhythms in gene expression
and rhythmically coordinates the physiology, metabolism and behavior in a wide range of …

Hsa-let-7f-1-3p targeting the circadian gene Bmal1 mediates intervertebral disc degeneration by regulating autophagy

L Mei, Y Zheng, X Gao, T Ma, B Xia, Y Hao, B Wei… - Pharmacological …, 2022 - Elsevier
The intervertebral disc has an intrinsic circadian rhythm, elimination of which leads to stress
in nucleus pulposus cells (NPCs), contributing to intervertebral disc degeneration (IDD) …