Changing color for photoprotection: the orange carotenoid protein

F Muzzopappa, D Kirilovsky - Trends in Plant Science, 2020 - cell.com
Under high irradiance, light becomes dangerous for photosynthetic organisms and they
must protect themselves. Cyanobacteria have developed a simple mechanism, involving a …

Optogenetic methods in plant biology

KR Konrad, S Gao, MD Zurbriggen… - Annual Review of Plant …, 2023 - annualreviews.org
Optogenetics is a technique employing natural or genetically engineered photoreceptors in
transgene organisms to manipulate biological activities with light. Light can be turned on or …

Structural framework for the understanding spectroscopic and functional signatures of the cyanobacterial Orange Carotenoid Protein families

NN Sluchanko, EG Maksimov, YB Slonimskiy… - International Journal of …, 2024 - Elsevier
Abstract The Orange Carotenoid Protein (OCP) is a unique photoreceptor crucial for
cyanobacterial photoprotection. Best studied Synechocystis sp. PCC 6803 OCP belongs to …

Microalgal protein AstaP is a potent carotenoid solubilizer and delivery module with a broad carotenoid binding repertoire

YB Slonimskiy, NA Egorkin, T Friedrich… - The FEBS …, 2022 - Wiley Online Library
Carotenoids are lipophilic substances with many biological functions, from coloration to
photoprotection. Being potent antioxidants, carotenoids have multiple biomedical …

The photocycle of orange carotenoid protein conceals distinct intermediates and asynchronous changes in the carotenoid and protein components

EG Maksimov, NN Sluchanko, YB Slonimskiy… - Scientific reports, 2017 - nature.com
Abstract The 35-kDa Orange Carotenoid Protein (OCP) is responsible for photoprotection in
cyanobacteria. It acts as a light intensity sensor and efficient quencher of phycobilisome …

OCP–FRP protein complex topologies suggest a mechanism for controlling high light tolerance in cyanobacteria

NN Sluchanko, YB Slonimskiy, EA Shirshin… - Nature …, 2018 - nature.com
In cyanobacteria, high light photoactivates the orange carotenoid protein (OCP) that binds to
antennae complexes, dissipating energy and preventing the destruction of the …

Reconstitution of the functional Carotenoid-Binding Protein from silkworm in E. coli

YB Slonimskiy, NA Egorkin, AA Ashikhmin… - International Journal of …, 2022 - Elsevier
Natural water-soluble carotenoproteins are promising antioxidant nanocarriers for
biomedical applications. The Carotenoid-Binding Protein from silkworm Bombyx mori …

Stages of OCP-FRP interactions in the regulation of photoprotection in cyanobacteria, part 1: time-resolved spectroscopy

GV Tsoraev, A Bukhanko, GS Budylin… - The Journal of …, 2023 - ACS Publications
Most cyanobacteria utilize a water-soluble Orange Carotenoid Protein (OCP) to protect their
light-harvesting complexes from photodamage. The Fluorescence Recovery Protein (FRP) is …

Interdomain interactions reveal the molecular evolution of the orange carotenoid protein

F Muzzopappa, A Wilson, D Kirilovsky - Nature plants, 2019 - nature.com
The photoactive orange carotenoid protein (OCP) is a blue-light intensity sensor involved in
cyanobacterial photoprotection. Three OCP families co-exist (OCPX, OCP1 and OCP2) …

Probing of carotenoid-tryptophan hydrogen bonding dynamics in the single-tryptophan photoactive Orange Carotenoid Protein

EG Maksimov, EA Protasova, GV Tsoraev… - Scientific reports, 2020 - nature.com
Abstract The photoactive Orange Carotenoid Protein (OCP) plays a key role in
cyanobacterial photoprotection. In OCP, a single non-covalently bound keto-carotenoid …