Many features of the environment have been found to exert an important influence on
cardiovascular disease (CVD) risk, progression, and severity. Changes in the environment …

The term epigenetics was first used to refer to the complex interactions between the genome
and the environment that are involved in development and differentiation in higher …

Lipid peroxidation (LPO) product accumulation in human tissues is a major cause of tissular
and cellular dysfunction that plays a major role in ageing and most age-related and …

Many epidemiological studies have indicated a protective role for a diet rich in fruits and
vegetables against the development and progression of cardiovascular disease (CVD), one …

Most explanations of the increase in life expectancy at older ages over history emphasize
the importance of medical and public health factors of a particular historical period. We …

The adverse outcomes on the offspring from maternal diabetes in pregnancy are
substantially documented. In this paper, we report main knowledge on impacts of maternal …

Nitric oxide (NO) is a molecule that has gained recognition as a crucial modulator of
vascular disease. NO has a number of intracellular effects that lead to vasorelaxation …

Atualmente sabemos que é possível obter uma redução na incidência de complicações da
aterosclerose com a adoção de um estilo de vida saudável e com o tratamento …

Using historical data from cohorts born before the 20th century in four northern European
countries, we show that increasing longevity and declining mortality in the elderly occurred …

The complex pathobiology underlying cardiovascular diseases (CVDs) has yet to be
explained. Aberrant epigenetic changes may result from alterations in enzymatic activities …