Bacterial quorum sensing in complex and dynamically changing environments

S Mukherjee, BL Bassler - Nature Reviews Microbiology, 2019 - nature.com
Quorum sensing is a process of bacterial cell-to-cell chemical communication that relies on
the production, detection and response to extracellular signalling molecules called …

Antibiotic resistance in Pseudomonas aeruginosa–Mechanisms, epidemiology and evolution

J Botelho, F Grosso, L Peixe - Drug resistance updates, 2019 - Elsevier
Antibiotics are powerful drugs used in the treatment of bacterial infections. The inappropriate
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …

[HTML][HTML] Bacterial exopolysaccharides as emerging bioactive macromolecules: from fundamentals to applications

N Kaur, P Dey - Research in microbiology, 2023 - Elsevier
Microbial exopolysaccharides (EPS) are extracellular carbohydrate polymers forming
capsules or slimy coating around the cells. EPS can be secreted by various bacterial genera …

[HTML][HTML] Physico-chemistry from initial bacterial adhesion to surface-programmed biofilm growth

V Carniello, BW Peterson, HC van der Mei… - Advances in colloid and …, 2018 - Elsevier
Biofilm formation is initiated by adhesion of individual bacteria to a surface. However,
surface adhesion alone is not sufficient to form the complex community architecture of a …

Short-range interactions govern the dynamics and functions of microbial communities

A Dal Co, S van Vliet, DJ Kiviet, S Schlegel… - Nature ecology & …, 2020 - nature.com
Communities of interacting microorganisms play important roles across all habitats on Earth.
These communities typically consist of a large number of species that perform different …

Short-range quorum sensing controls horizontal gene transfer at micron scale in bacterial communities

J van Gestel, T Bareia, B Tenennbaum… - Nature …, 2021 - nature.com
In bacterial communities, cells often communicate by the release and detection of small
diffusible molecules, a process termed quorum-sensing. Signal molecules are thought to …

The biogeography of infection revisited

S Azimi, GR Lewin, M Whiteley - Nature Reviews Microbiology, 2022 - nature.com
Many microbial communities, including those involved in chronic human infections, are
patterned at the micron scale. In this Review, we summarize recent work that has defined the …

Recent advances in therapeutic targets identification and development of treatment strategies towards Pseudomonas aeruginosa infections

DRA Sanya, D Onésime, G Vizzarro, N Jacquier - BMC microbiology, 2023 - Springer
The opportunistic human pathogen Pseudomonas aeruginosa is the causal agent of a wide
variety of infections. This non-fermentative Gram-negative bacillus can colonize zones …

Quantitative Framework for Model Evaluation in Microbiology Research Using Pseudomonas aeruginosa and Cystic Fibrosis Infection as a Test Case

DM Cornforth, FL Diggle, JA Melvin, JM Bomberger… - MBio, 2020 - Am Soc Microbiol
Laboratory models are a cornerstone of modern microbiology, but the accuracy of these
models has not been systematically evaluated. As a result, researchers often choose models …

Application of a quantitative framework to improve the accuracy of a bacterial infection model

GR Lewin, A Kapur, DM Cornforth… - Proceedings of the …, 2023 - National Acad Sciences
Laboratory models are critical to basic and translational microbiology research. Models
serve multiple purposes, from providing tractable systems to study cell biology to allowing …