Biotechnological interventions for harnessing podophyllotoxin from plant and fungal species: current status, challenges, and opportunities for its commercialization

A Kumari, D Singh, S Kumar - Critical reviews in biotechnology, 2017 - Taylor & Francis
Podophyllotoxin is an aryltetralin lignan synthesized in several plant species, which is used
in chemotherapies for cancers and tumor treatment. More potent semisynthetic derivatives of …

Medicinal plant research at crossroads: biotechnological approaches for conservation, production and stability in tissue cultures and regenerated plants

M Halder, A Majumder, S Ray, S Jha - Medicinal Plants: Domestication …, 2021 - Springer
Medicinal plants are treasures of nature with almost never-ending resource of unlimited,
diverse, complex and valuable natural compounds with a variety of pharmacological …

Factors influencing podophyllotoxin production in adventitious root culture of Podophyllum hexandrum Royle

M Rajesh, G Sivanandhan, M Arun… - Acta physiologiae …, 2014 - Springer
To determine the possibility of generating the Podophyllotoxin accumulation using
Podophyllum hexandrum adventitious roots derived from root segments, several nutrient …

In vitro propagation from seeds and enhanced synthesis of podophyllotoxin from root callus of SinoPodophyllum hexandrum Royle TS Ying (Himalayan Mayapple) …

N Sharma, M Thakur, P Sharma, B Dutt… - Industrial Crops and …, 2022 - Elsevier
In vitro propagation and secondary metabolite production are the vital biotechnological
approaches for the multiplication, conservation, and phytochemicals production from rare …

In vitro propagation from rhizomes, molecular evaluation and podophyllotoxin production in Himalayan May Apple (Sinopodophyllum hexandrum Royle TS Ying): an …

N Sharma, M Thakur, P Sharma, YP Sharma… - Plant Cell, Tissue and …, 2022 - Springer
The present study reports an optimized single step protocol for high frequency in vitro
propagation through rhizome buds, molecular analysis and podophyllotoxin production in …

An efficient in vitro system for somatic embryogenesis and podophyllotoxin production in Podophyllum hexandrum Royle

M Rajesh, G Sivanandhan, M Jeyaraj, R Chackravarthy… - Protoplasma, 2014 - Springer
Podophyllum hexandrum Royle known as Indian mayapple is an important medicinal plant
found only in higher altitudes (2,700 to 4,200 m) of the Himalayas. The highly valued …

[PDF][PDF] In vitro micropropagation using corm bud explants: an endangered medicinal plant of Gloriosa superba L

A Arumugam, K Gopinath - Asian J Biotechnol, 2012 - academia.edu
A ISTRA ("|" An efficient protocol was developed in vitro micropropagation of Gloriosa
superba by using corm bud explant. MS basal medium supplemented with different …

Agrobacterium-mediated transformation of the medicinal plant Podophyllum hexandrum Royle (syn. P. emodi Wall. ex Hook.f. & Thomas)

M Rajesh, M Jeyaraj, G Sivanandhan… - Plant Cell, Tissue and …, 2013 - Springer
An efficient Agrobacterium-mediated genetic transformation method has been developed for
the medicinal plant Podophyllum hexandrum Royle, an important source of the anticancer …

Optimization of surface sterilization process of selected dye-yielding plants for isolation of bacterial endophytes

B Khanam, R Chandra - Applications of biotechnology for sustainable …, 2017 - Springer
Sterilizing agents, such as sodium hypochlorite (NaOCl), hydrogen peroxide (H 2 O 2),
mercuric chloride (HgCl 2), and ethanol (C 2 H 5 OH), are commonly used in plant tissue …

Unraveling Medicinal Plant Chemical Diversity for Novel Drug Discovery Through Biotechnological Interventions

MZ Gul, MY Bhat, EP Ryan… - Omics Studies of …, 2023 - api.taylorfrancis.com
The plant kingdom is one of the earth's prime life-supporting systems. In addition to the
apparent nutritional benefits, the therapeutic attributes of plants have been established since …