Neurogenesis continues well beyond embryonic and early postnatal ages in three areas of
the nervous system. The subgranular zone supplies new neurons to the dentate gyrus of the …

Random monoallelic expression (RME) of genes represents a striking example of how
stochastic molecular processes can result in cellular heterogeneity. Recent transcriptome …

The presence of active neurogenic niches in adult humans is controversial. We focused
attention to the human olfactory neuroepithelium, an extracranial site supplying input to the …

The genome is partitioned into topologically associated domains and genomic
compartments with shared chromatin valence. This architecture is constrained by the DNA …

SARS-CoV-2 infects less than 1% of cells in the human body, yet it can cause severe
damage in a variety of organs. Thus, deciphering the non-cell-autonomous effects of SARS …

Olfactory receptor (OR) choice provides an extreme example of allelic competition for
transcriptional dominance, where every olfactory neuron stably transcribes one of …

One of the major challenges in modern biology is to understand how the molecular
components of a living cell operate in a highly noisy environment. What are the specific …

INTRODUCTION The mammalian nose is arguably the best chemical sensor on the planet,
able to detect and discriminate among a large and diverse repertoire of mostly small …

INTRODUCTION Changes in histone posttranslational modifications are associated with
epigenetic states that define distinct patterns of gene expression. Whereas sequence …

Principles of Neurobiology, Second Edition presents the major concepts of neuroscience
with an emphasis on how we know what we know. The text is organized around a series of …