Inflammation plays an important role in the response to danger signals arising from damage
to our body and in restoring homeostasis. Dysregulated inflammatory responses occur in …

Macrophages, which are key cellular components of the liver, have emerged as essential
players in the maintenance of hepatic homeostasis and in injury and repair processes in …

The progression of chronic liver diseases (CLD), irrespective of etiology, involves chronic
parenchymal injury, persistent activation of inflammatory response as well as sustained …

Effective delivery of therapeutic and diagnostic nanoparticles is dependent on their ability to
accumulate in diseased tissues. However, most nanoparticles end up in liver macrophages …

Macrophages represent a key cellular component of the liver, and are essential for
maintaining tissue homeostasis and ensuring rapid responses to hepatic injury. Our …

Our view on liver macrophages in the context of health and disease has been reformed by
the recognition of a remarkable heterogeneity of phagocytes in the liver. Liver macrophages …

Nano-formulating dexamethasone, and administering it via intravenous injection or
inhalation, may help to improve anti-COVID-19 treatment efficacy by targeting the potent …

Macrophages represent a major cell type of innate immunity and have emerged as a critical
player and therapeutic target in many chronic inflammatory diseases. Hepatic macrophages …

Hepatic macrophages play a central role in maintaining homeostasis in the liver, as well as
in the initiation and progression of liver diseases. Hepatic macrophages are mainly derived …

Dexamethasone (DEX) has been widely used to treat a variety of diseases, including
autoimmune diseases, allergies, ocular disorders, cancer, and, more recently, COVID-19 …