Osteoporosis, is the most common bone disorder worldwide characterized by low bone
mineral density, leaving affected bones vulnerable to fracture. Bone homeostasis depends …

Ferroptosis is an iron-dependent regulated cell death driven by excessive lipid peroxidation.
Inflammation is one common and effective physiological event that protects against various …

Iron is a critical metal for several vital biological processes. Most of the body's iron is bound
to hemoglobin in erythrocytes. Iron from senescent red blood cells is recycled by …

Ferroptosis has recently been demonstrated to be a novel regulated non-apoptotic cell
death characterized by iron-dependence and the accumulation of lipid peroxidation that …

Ferroptosis is a form of lipid peroxidation-induced cell death that can be regulated in many
ways, from altering the activity of antioxidant enzymes to the level of transcription factors …

Background Guidelines on heart failure (HF) define iron deficiency (ID) as a serum ferritin<
100 ng/mL or, when 100-299 ng/mL, a transferrin saturation (TSAT)< 20%. Inflammation …

Metals such as iron, manganese, copper, and zinc are recognized as essential trace
elements. These trace metals play critical roles in development, growth, and metabolism …

Iron is an essential micronutrient for a myriad of physiological processes in the body beyond
erythropoiesis. Iron deficiency (ID) is a common comorbidity in patients with heart failure …

Polyphenols are an important component of plant-derived food with a wide spectrum of
beneficial effects on human health. For many years, they have aroused great interest …

Obesity is an excessive adipose tissue accumulation that may have detrimental effects on
health. Particularly, childhood obesity has become one of the main public health problems in …