Introduction Certain HLA variants are associated with an increased risk of hypersensitivity
reactions to specific drugs. Both the Clinical Pharmacogenetics Implementation Consortium …

British Association of Dermatologists' guidelines for the management of Stevens–Johnson
syndrome/toxic epidermal necrolysis in children and young people, 2018 | British Journal of …

Aggregated risk of carbamazepine (CBZ)‐induced cutaneous adverse drug reactions
(cADRs) with different HLA variants are unclear and limited in terms of the power of studies …

Adverse drug reaction (ADR) is a pressing health problem, and one of the main reasons for
treatment failure with antiepileptic drugs. This has become apparent in the event of severe …

Background: The relationship between HLA-B* 15: 02 and Severe Cutaneous Adverse
Reactions was rigorously examined in Japanese, Han Chinese, Thais, and Caucasians …

Aims Despite the availability of newer antiseizure medications, carbamazepine (CBZ)
remains the gold standard. However, patients of Asian ancestry are susceptible to CBZ …

The last review on epilepsy in Southeast Asian (SEA) countries was reported in 1997. This
review aimed to update the understanding of epilepsy management in this region over the …

Purpose This umbrella review was conducted to summarize the association between HLA*
1502 allele with antiepileptic induced Stevens–Johnson syndrome (SJS) and toxic …

Introduction Adverse skin reactions due to drugs such as Stevens Johnson Syndrome (SJS)
and Toxic Epidermal Necrolysis (TEN) occur in 3% of people receiving anti epileptic drugs …

Purpose This umbrella review was conducted to summarize the evidence between
association between HLA* 1502 allele with various antiepileptic induced Stevens-Johnson …