Bioactive compounds, including active pharmaceutical ingredients (APIs), are often chiral
molecules where stereoisomers have different biological and therapeutic activity …

Like many biological compounds, proteins are found primarily in their homochiral form.
However, homochirality is not guaranteed throughout life. Determining their chiral …

Enantioselective chromatography has been the preferred technique for the determination of
enantiomeric excess across academia and industry. Although sequential multicolumn …

This work presents an advanced analytical platform for untargeted enantioselective amino
acid analysis (eAAA) by comprehensive achiral× chiral 2D-LC hyphenated to ESI-QTOF …

The retention behavior of small molecules and N-protected amino acids on a zwitterionic
teicoplanin chiral stationary phase (CSP), prepared on superficially porous particles (SPPs) …

In this work, we present a unique, robust and fully automated analytical platform technology
for the enantioselective amino acid analysis using a multiple heart cutting RPLC-enantio …

High throughput experimentation is a growing and evolving field that allows to execute
dozens to several thousands of experiments per day with relatively limited resources …

Hydrophilic interaction liquid chromatography (HILIC) today is a well-known and largely
applied technique to analyse polar compounds such as pharmaceuticals, metabolites …

Chiral separation techniques play a crucial role in the pharmaceutical industry, where the
enantiomeric purity of drugs can have a significant impact on their efficacy and safety …

Since their discovery, the Pirkle-type chiral stationary phases, and in particular the Whelk-
O1, have been used in a large number of applications and theoretical studies. Although they …