Technology of deep brain stimulation: current status and future directions

JK Krauss, N Lipsman, T Aziz, A Boutet… - Nature Reviews …, 2021 - nature.com
Deep brain stimulation (DBS) is a neurosurgical procedure that allows targeted circuit-based
neuromodulation. DBS is a standard of care in Parkinson disease, essential tremor and …

Insights and opportunities for deep brain stimulation as a brain circuit intervention

WJ Neumann, A Horn, AA Kühn - Trends in Neurosciences, 2023 - cell.com
Deep brain stimulation (DBS) is an effective treatment and has provided unique insights into
the dynamic circuit architecture of brain disorders. This Review illustrates our current …

Population-specific neuromodulation prolongs therapeutic benefits of deep brain stimulation

TA Spix, S Nanivadekar, N Toong, IM Kaplow, BR Isett… - Science, 2021 - science.org
Symptoms of neurological diseases emerge through the dysfunction of neural circuits whose
diffuse and intertwined architectures pose serious challenges for delivering therapies. Deep …

Modelling and prediction of the dynamic responses of large-scale brain networks during direct electrical stimulation

Y Yang, S Qiao, OG Sani, JI Sedillo… - Nature biomedical …, 2021 - nature.com
Direct electrical stimulation can modulate the activity of brain networks for the treatment of
several neurological and neuropsychiatric disorders and for restoring lost function. However …

Neuromodulation in the restoration of function after spinal cord injury

ND James, SB McMahon, EC Field-Fote… - The Lancet …, 2018 - thelancet.com
Neuromodulation, the use of electrical interfaces to alter neuronal activity, has been
successful as a treatment approach in several neurological disorders, including deep brain …

Proceedings of the eighth annual deep brain stimulation think tank: advances in optogenetics, ethical issues affecting DBS research, neuromodulatory approaches for …

V Vedam-Mai, K Deisseroth, J Giordano… - Frontiers in Human …, 2021 - frontiersin.org
We estimate that 208,000 deep brain stimulation (DBS) devices have been implanted to
address neurological and neuropsychiatric disorders worldwide. DBS Think Tank presenters …

Implantable pulse generators for deep brain stimulation: challenges, complications, and strategies for practicality and longevity

C Sarica, C Iorio-Morin, DH Aguirre-Padilla… - Frontiers in Human …, 2021 - frontiersin.org
Deep brain stimulation (DBS) represents an important treatment modality for movement
disorders and other circuitopathies. Despite their miniaturization and increasing …

Phase-dependent suppression of beta oscillations in Parkinson's disease patients

AB Holt, E Kormann, A Gulberti… - Journal of …, 2019 - Soc Neuroscience
Synchronized oscillations within and between brain areas facilitate normal processing, but
are often amplified in disease. A prominent example is the abnormally sustained beta …

Deep brain stimulation: a review of the open neural engineering challenges

M Vissani, IU Isaias, A Mazzoni - Journal of neural engineering, 2020 - iopscience.iop.org
Objective. Deep brain stimulation (DBS) is an established and valid therapy for a variety of
pathological conditions ranging from motor to cognitive disorders. Still, much of the DBS …

Past, present, and future of deep brain stimulation: hardware, software, imaging, physiology and novel approaches

J Frey, J Cagle, KA Johnson, JK Wong… - Frontiers in …, 2022 - frontiersin.org
Deep brain stimulation (DBS) has advanced treatment options for a variety of neurologic and
neuropsychiatric conditions. As the technology for DBS continues to progress, treatment …