SVOC exposure indoors: fresh look at dermal pathways
CJ Weschler, WW Nazaroff - Indoor air, 2012 - Wiley Online Library
This paper critically examines indoor exposure to semivolatile organic compounds (SVOCs)
via dermal pathways. First, it demonstrates that–in central tendency–an SVOC's abundance …
via dermal pathways. First, it demonstrates that–in central tendency–an SVOC's abundance …
Mathematical models of skin permeability: an overview
Mathematical models of skin permeability play an important role in various fields including
prediction of transdermal drug delivery and assessment of dermal exposure to industrial …
prediction of transdermal drug delivery and assessment of dermal exposure to industrial …
[HTML][HTML] Molecular size as the main determinant of solute maximum flux across the skin
BM Magnusson, YG Anissimov, SE Cross… - Journal of Investigative …, 2004 - Elsevier
One of the most important determinants of dermatological and systemic penetration after
topical application is the delivery or flux of solutes into or through the skin. The maximum …
topical application is the delivery or flux of solutes into or through the skin. The maximum …
Parallel artificial membrane permeability assay: a new membrane for the fast prediction of passive human skin permeability
G Ottaviani, S Martel, PA Carrupt - Journal of medicinal chemistry, 2006 - ACS Publications
This work was devoted to the search for new artificial membranes allowing a rapid
evaluation of passive human skin permeation of compounds with a parallel artificial …
evaluation of passive human skin permeation of compounds with a parallel artificial …
Mathematical and pharmacokinetic modelling of epidermal and dermal transport processes
YG Anissimov, OG Jepps, Y Dancik… - Advanced Drug Delivery …, 2013 - Elsevier
Topical delivery to the various regions of the skin and underlying tissues, transdermal drug
delivery and dermal exposure to environmental chemicals are important areas of research …
delivery and dermal exposure to environmental chemicals are important areas of research …
Quantitative structure-skin permeability relationships
This paper reviews in silico models currently available for the prediction of skin permeability.
A comprehensive discussion on the developed methods is presented, focusing on …
A comprehensive discussion on the developed methods is presented, focusing on …
[HTML][HTML] Evaluating molecular properties involved in transport of small molecules in stratum corneum: A quantitative structure-activity relationship for skin permeability
CP Chen, CC Chen, CW Huang, YC Chang - Molecules, 2018 - mdpi.com
The skin permeability (Kp) defines the rate of a chemical penetrating across the stratum
corneum. This value is widely used to quantitatively describe the transport of molecules in …
corneum. This value is widely used to quantitatively describe the transport of molecules in …
Quantitative structure-permeation relationships (QSPeRs) to predict skin permeation: a critical evaluation
S Geinoz, RH Guy, B Testa, PA Carrupt - Pharmaceutical Research, 2004 - Springer
Purpose. Development of reliable mathematical models to predict skin permeability remains
a challenging objective. This article examines some of the existing algorithms and critically …
a challenging objective. This article examines some of the existing algorithms and critically …
[HTML][HTML] Effect of drug loading method and drug physicochemical properties on the material and drug release properties of poly (ethylene oxide) hydrogels for …
RSH Wong, K Dodou - Polymers, 2017 - mdpi.com
Novel poly (ethylene oxide)(PEO) hydrogel films were synthesized via UV cross-linking with
pentaerythritol tetra-acrylate (PETRA) as cross-linking agent. The purpose of this work was …
pentaerythritol tetra-acrylate (PETRA) as cross-linking agent. The purpose of this work was …
Emerging investigator series: the role of chemical properties in human exposure to environmental chemicals
One of the ultimate goals of environmental exposure science is to mechanistically
understand how chemical properties and human behavior interactively determine human …
understand how chemical properties and human behavior interactively determine human …