Altered expression of secreted factors by tumor cells or cells of the tumor microenvironment
is a key event in cancer development and progression. In the last decade, emerging …

Bone Morphogenetic Protein (BMP) patterns the dorsal–ventral (DV) embryonic axis in all
vertebrates, but it is unknown how cells along the DV axis interpret and translate the …

During coordinated development of two neighboring organs from the same germ layer, how
precursors of one organ resist the inductive signals of the other to avoid being misinduced to …

Zebrafish have become a powerful model of mammalian lipoprotein metabolism and lipid
cell biology. Most key proteins involved in lipid metabolism, including cholesteryl ester …

Nobiletin, a dietary citrus flavonoid, exerts biological activities against hyperlipidemia,
obesity, and atherosclerotic cardiovascular diseases (ASCVDs). The aim of this study was to …

The liver is a crucial center in the regulation of energy homeostasis under starvation.
Although downregulation of mammalian target of rapamycin complex 1 (mTORC1) has been …

Clinical depression is one of the most common and debilitating psychiatric disorders and
contributes to increased risks of disability and suicide. Differentially expressed serum …

Owing to the many physiological functions of glutathione, fluorescent sensing systems that
selectively and sensitively detect this biothiol in biological systems are in great demand. In …

Background & aims Hepassocin (HPS) is a hepatotrophic growth factor that specifically
stimulates hepatocyte proliferation and promotes liver regeneration after liver damage. In …

Lipoprotein kinetics are a crucial factor in understanding lipoprotein metabolism since a
prolonged time in circulation can contribute to the atherogenic character of apolipoprotein-B …