Simple Summary Hepatocellular carcinoma (HCC) is an aggressive human cancer and is
caused as consequences of chronic liver diseases. Although HCC is more common in …

The global prevalence of nonalcoholic fatty liver disease (NAFLD) continues to rise, yet
effective treatments are lacking due to the complex pathogenesis of this disease. Although …

Abstract Rationale: Nonalcoholic steatohepatitis (NASH), as one of the key stages in the
development of nonalcoholic fatty liver disease (NAFLD), can directly progress to HCC, but …

Epigenetics, an inheritable phenomenon, which influences the expression of gene without
altering the DNA sequence, offers a new perspective on the pathogenesis of hepatocellular …

Hepatocellular carcinoma (HCC) is the sixth most common cancer in the world and is
usually caused by viral hepatitis (HBV and HCV), alcoholic, and non-alcoholic fatty liver …

Abstract Nuclear protein‑1 (NUPR1) is also known as Com‑1 or p8. It is a protein primarily
found in the nucleus of various cells, including cancer cells, and it has been found to play an …

Activation of hepatic stellate cells (HSC) is a hallmark event in liver fibrosis. Accumulation of
reactive oxygen species (ROS) serves as a driving force for HSC activation. The regulatory …

The pathogenesis of hepatocellular carcinoma (HCC) is a multifactorial process that has not
yet been fully investigated. Autophagy and apoptosis are two important cellular pathways …

LncRNA ANCR plays important roles in the modulation of epithelial mesenchymal transition
(EMT) and tumour metastasis in many tumours. However, the role of ANCR in regulating …

Hepatocellular carcinoma (HCC) is the fastest-rising cause of cancer-related death in the
United States. Recent epidemiological studies have identified nonalcoholic steatohepatitis …