[HTML][HTML] Magnetic iron oxide nanoparticles for imaging, targeting and treatment of primary and metastatic tumors of the brain

LL Israel, A Galstyan, E Holler, JY Ljubimova - Journal of Controlled …, 2020 - Elsevier
Magnetic nanoparticles in general, and iron oxide nanoparticles in particular, have been
studied extensively during the past 20 years for numerous biomedical applications. The …

Recent advances in metal nanoparticles in cancer therapy

A Sharma, AK Goyal, G Rath - Journal of drug targeting, 2018 - Taylor & Francis
Metal nanoparticles (NPs) may have the potential to overcome problems related to
conventional chemotherapy. Metal NPs reported to play a beneficial and powerful role in …

miRNA nanotherapeutics for cancer

A Ganju, S Khan, BB Hafeez, SW Behrman… - Drug discovery today, 2017 - Elsevier
Highlights•MicroRNAs play a major role in cancer.•Several clinical trials with microRNA are
reported for cancer treatment.•Delivery of microRNA encounters several challenges.•We …

[HTML][HTML] Role of miRNAs in neurodegeneration: From disease cause to tools of biomarker discovery and therapeutics

B Roy, E Lee, T Li, M Rampersaud - Genes, 2022 - mdpi.com
Neurodegenerative diseases originate from neuronal loss in the central nervous system
(CNS). These debilitating diseases progress with age and have become common due to an …

Role of long non-coding RNAs (lncRNAs) in cancer: from subcellular localization to nanoparticles (NPs)-mediated targeted regulation

C Wei, Y Xu, Q Shen, R Li, X Xiao, PE Saw… - … Therapy-Nucleic Acids, 2023 - cell.com
Long non-coding RNAs (lncRNAs) are a class of RNA transcripts more than 200 nucleotides
in length that play crucial roles in cancer development and progression. With the rapid …

Nanocarriers for microRNA delivery in cancer medicine

I Fernandez-Piñeiro, I Badiola, A Sanchez - Biotechnology advances, 2017 - Elsevier
The number of deaths caused by cancer is expected to increase partly due to the lack of
selectivity and undesirable systemic effects of current treatments. Advances in the …

Opportunities and challenges of using high-sensitivity nanobiosensors to detect long noncoding RNAs: A preliminary review

S Sargazi, M Mukhtar, A Rahdar, M Bilal… - International Journal of …, 2022 - Elsevier
The two types ofncRNAs, including microRNAs (miRNAs) and long noncoding RNAs
(lncRNAs), are responsible for several biological processes within cells, such as the immune …

[HTML][HTML] Getting miRNA therapeutics into the target cells for neurodegenerative diseases: a mini-review

MM Wen - Frontiers in molecular neuroscience, 2016 - frontiersin.org
miRNAs play important roles in modulating gene expression in varying cellular processes
and disease pathogenesis, including neurodegenerative diseases. Several miRNAs are …

Redox‐Responsive Polymeric Nanoparticle for Nucleic Acid Delivery and Cancer Therapy: Progress, Opportunities, and Challenges

L Xu, Y Cao, Y Xu, R Li, X Xu - Macromolecular Bioscience, 2024 - Wiley Online Library
Cancer development and progression of cancer are closely associated with the activation of
oncogenes and loss of tumor suppressor genes. Nucleic acid drugs (eg, siRNA, mRNA, and …

[HTML][HTML] Nanoparticles target early-stage breast cancer metastasis in vivo

E Goldman, A Zinger, D Da Silva, Z Yaari… - …, 2017 - iopscience.iop.org
Despite advances in cancer therapy, treating cancer after it has metastasized remains an
unmet clinical challenge. In this study we demonstrate that 100 nm liposomes target triple …