[HTML][HTML] Magnetic iron oxide nanoparticles for imaging, targeting and treatment of primary and metastatic tumors of the brain
LL Israel, A Galstyan, E Holler, JY Ljubimova - Journal of Controlled …, 2020 - Elsevier
Magnetic nanoparticles in general, and iron oxide nanoparticles in particular, have been
studied extensively during the past 20 years for numerous biomedical applications. The …
studied extensively during the past 20 years for numerous biomedical applications. The …
Recent advances in metal nanoparticles in cancer therapy
Metal nanoparticles (NPs) may have the potential to overcome problems related to
conventional chemotherapy. Metal NPs reported to play a beneficial and powerful role in …
conventional chemotherapy. Metal NPs reported to play a beneficial and powerful role in …
miRNA nanotherapeutics for cancer
Highlights•MicroRNAs play a major role in cancer.•Several clinical trials with microRNA are
reported for cancer treatment.•Delivery of microRNA encounters several challenges.•We …
reported for cancer treatment.•Delivery of microRNA encounters several challenges.•We …
[HTML][HTML] Role of miRNAs in neurodegeneration: From disease cause to tools of biomarker discovery and therapeutics
B Roy, E Lee, T Li, M Rampersaud - Genes, 2022 - mdpi.com
Neurodegenerative diseases originate from neuronal loss in the central nervous system
(CNS). These debilitating diseases progress with age and have become common due to an …
(CNS). These debilitating diseases progress with age and have become common due to an …
Role of long non-coding RNAs (lncRNAs) in cancer: from subcellular localization to nanoparticles (NPs)-mediated targeted regulation
C Wei, Y Xu, Q Shen, R Li, X Xiao, PE Saw… - … Therapy-Nucleic Acids, 2023 - cell.com
Long non-coding RNAs (lncRNAs) are a class of RNA transcripts more than 200 nucleotides
in length that play crucial roles in cancer development and progression. With the rapid …
in length that play crucial roles in cancer development and progression. With the rapid …
Nanocarriers for microRNA delivery in cancer medicine
I Fernandez-Piñeiro, I Badiola, A Sanchez - Biotechnology advances, 2017 - Elsevier
The number of deaths caused by cancer is expected to increase partly due to the lack of
selectivity and undesirable systemic effects of current treatments. Advances in the …
selectivity and undesirable systemic effects of current treatments. Advances in the …
Opportunities and challenges of using high-sensitivity nanobiosensors to detect long noncoding RNAs: A preliminary review
The two types ofncRNAs, including microRNAs (miRNAs) and long noncoding RNAs
(lncRNAs), are responsible for several biological processes within cells, such as the immune …
(lncRNAs), are responsible for several biological processes within cells, such as the immune …
[HTML][HTML] Getting miRNA therapeutics into the target cells for neurodegenerative diseases: a mini-review
MM Wen - Frontiers in molecular neuroscience, 2016 - frontiersin.org
miRNAs play important roles in modulating gene expression in varying cellular processes
and disease pathogenesis, including neurodegenerative diseases. Several miRNAs are …
and disease pathogenesis, including neurodegenerative diseases. Several miRNAs are …
Redox‐Responsive Polymeric Nanoparticle for Nucleic Acid Delivery and Cancer Therapy: Progress, Opportunities, and Challenges
L Xu, Y Cao, Y Xu, R Li, X Xu - Macromolecular Bioscience, 2024 - Wiley Online Library
Cancer development and progression of cancer are closely associated with the activation of
oncogenes and loss of tumor suppressor genes. Nucleic acid drugs (eg, siRNA, mRNA, and …
oncogenes and loss of tumor suppressor genes. Nucleic acid drugs (eg, siRNA, mRNA, and …
[HTML][HTML] Nanoparticles target early-stage breast cancer metastasis in vivo
Despite advances in cancer therapy, treating cancer after it has metastasized remains an
unmet clinical challenge. In this study we demonstrate that 100 nm liposomes target triple …
unmet clinical challenge. In this study we demonstrate that 100 nm liposomes target triple …