From Levinthalto pathways to funnels Page 1 TS 9 1997 Nature Publishing Group http://www.nature.com/nsmb
perspective From Levinthalto pathways to funnels Ken A. Dill and Hue Sun Chan A new …

This paper surveys the emerging role of statistical mechanics and polymer theory in protein
folding. In the polymer perspective, the folding code is more a solvation code than a code of …

Recent research has provided an abundance of new information on membrane
biochemistry. Now more than ever, it is essential to update our current understanding of …

The lipocalin family became established shortly after the structural similarity was noted
between plasma retinol binding protein and the bovine milk protein, β-lactoglobulin. During …

Among various alcohols, those substituted with fluorine, such as 2, 2, 2-trifluoroethanol
(TFE) or 3, 3, 3, 3 ', 3 ', 3 '-hexafluoro-2-propanol (HFIP), have a marked potential to induce …

We use two simple models and the energy landscape perspective to study protein folding
kinetics. A major challenge has been to use the landscape perspective to interpret …

Detailed analysis of the effects of alcohols on proteins and peptides is important because of
its wide range of applications in many fields. Whereas melittin, a major component of …

It is generally assumed that folding intermediates contain partially formed native-like
secondary structures. However, if we consider the fact that the conformational stability of the …

The strong coupling between secondary and tertiary structure formation in protein folding is
neglected in most structure prediction methods. In this work we investigate the extent to …

Although bovine β‐lactoglobulin assumes a monomeric native structure at pH 3 in the
absence of salt, the addition of salts stabilizes the dimer. Thermodynamics of the monomer …