Biliary atresia

JL Hartley, M Davenport, DA Kelly - The Lancet, 2009 - thelancet.com
Biliary atresia is a rare disease of infancy, which has changed within 30 years from being
fatal to being a disorder for which effective palliative surgery or curative liver transplantation …

Biliary atresia: a comprehensive review

B Lakshminarayanan, M Davenport - Journal of autoimmunity, 2016 - Elsevier
Biliary atresia presents as an obliterative cholangiopathy with neonatal jaundice and pale
stools. The disease exhibits aetiological heterogeneity with a multiplicity of potential …

Pathogenesis of biliary atresia: defining biology to understand clinical phenotypes

A Asai, A Miethke, JA Bezerra - Nature reviews Gastroenterology & …, 2015 - nature.com
Biliary atresia is a severe cholangiopathy of early infancy that destroys extrahepatic bile
ducts and disrupts bile flow. With a poorly defined disease pathogenesis, treatment consists …

Pathogenesis and outcome of biliary atresia: current concepts

RJ Sokol, C Mack, MR Narkewicz… - Journal of pediatric …, 2003 - journals.lww.com
Neonatal cholestatic disorders are a group of hepatobiliary diseases occurring within the
first 3 months of life. Bile flow is impaired, and patients have conjugated hyperbilirubinemia …

[PDF][PDF] Biliary atresia: current concepts and research directions. Summary of a symposium

WF Balistreri, R Grand, JH Hoofnagle, FJ Suchy… - …, 1996 - Wiley Online Library
Biliary atresia (BA) is the end result of a destructive, inflammatory process that affects intra‐
and extrahepatic bile ducts, leading to fibrosis and obliteration of the biliary tract with the …

[PDF][PDF] Screening and outcomes in biliary atresia: summary of a National Institutes of Health workshop

RJ Sokol, RW Shepherd, R Superina, JA Bezerra… - …, 2007 - Wiley Online Library
Biliary atresia is the most common cause of end‐stage liver disease in the infant and is the
leading pediatric indication for liver transplantation in the United States. Earlier diagnosis (< …

Innate immunity and pathogenesis of biliary atresia

A Ortiz-Perez, B Donnelly, H Temple, G Tiao… - Frontiers in …, 2020 - frontiersin.org
Biliary atresia (BA) is a devastating fibro-inflammatory disease characterized by the
obstruction of extrahepatic and intrahepatic bile ducts in infants that can have fatal …

The anatomic pattern of biliary atresia identified at time of Kasai hepatoportoenterostomy and early postoperative clearance of jaundice are significant predictors of …

R Superina, JC Magee, ML Brandt, PJ Healey… - Annals of …, 2011 - journals.lww.com
Objective: The goals of this study were to describe the clinical and anatomic features of
infants undergoing Kasai portoenterostomy (KPE) for biliary atresia (BA) and to examine …

Identification of a plant isoflavonoid that causes biliary atresia

K Lorent, W Gong, KA Koo… - Science translational …, 2015 - science.org
Biliary atresia (BA) is a rapidly progressive and destructive fibrotic disorder of unknown
etiology affecting the extrahepatic biliary tree of neonates. Epidemiological studies suggest …

Aetiology of biliary atresia: what is actually known?

C Petersen, M Davenport - Orphanet journal of rare diseases, 2013 - Springer
Biliary atresia (BA) is a rare disease of unknown etiology and unpredictable outcome, even
when there has been timely diagnosis and exemplary surgery. It has been the commonest …