The role of insufficient sleep and circadian misalignment in obesity

JP Chaput, AW McHill, RC Cox, JL Broussard… - Nature Reviews …, 2023 - nature.com
Traditional risk factors for obesity and the metabolic syndrome, such as excess energy
intake and lack of physical activity, cannot fully explain the high prevalence of these …

The emerging link between cancer, metabolism, and circadian rhythms

S Masri, P Sassone-Corsi - Nature medicine, 2018 - nature.com
The circadian clock is a complex cellular mechanism that, through the control of diverse
metabolic and gene expression pathways, governs a large array of cyclic physiological …

Early time-restricted feeding improves 24-hour glucose levels and affects markers of the circadian clock, aging, and autophagy in humans

H Jamshed, RA Beyl, DL Della Manna, ES Yang… - Nutrients, 2019 - mdpi.com
Time-restricted feeding (TRF) is a form of intermittent fasting that involves having a longer
daily fasting period. Preliminary studies report that TRF improves cardiometabolic health in …

Time‐restricted feeding improves glucose tolerance in men at risk for type 2 diabetes: a randomized crossover trial

AT Hutchison, P Regmi, ENC Manoogian… - …, 2019 - Wiley Online Library
Objective This study aimed to assess the effects of 9‐hour time‐restricted feeding (TRF),
early (TRFe) or delayed (TRFd), on glucose tolerance in men at risk for type 2 diabetes …

Circadian regulation of glucose, lipid, and energy metabolism in humans

E Poggiogalle, H Jamshed, CM Peterson - Metabolism, 2018 - Elsevier
The circadian system orchestrates metabolism in daily 24-hour cycles. Such rhythms
organize metabolism by temporally separating opposing metabolic processes and by …

Circadian rhythm and sleep disruption: causes, metabolic consequences, and countermeasures

GDM Potter, DJ Skene, J Arendt, JE Cade… - Endocrine …, 2016 - academic.oup.com
Abstract Circadian (∼ 24-hour) timing systems pervade all kingdoms of life and temporally
optimize behavior and physiology in humans. Relatively recent changes to our …

[HTML][HTML] Microbiota diurnal rhythmicity programs host transcriptome oscillations

CA Thaiss, M Levy, T Korem, L Dohnalová, H Shapiro… - Cell, 2016 - cell.com
The intestinal microbiota undergoes diurnal compositional and functional oscillations that
affect metabolic homeostasis, but the mechanisms by which the rhythmic microbiota …

Lifestyle recommendations for the prevention and management of metabolic syndrome: an international panel recommendation

P Pérez-Martínez, DP Mikhailidis, VG Athyros… - Nutrition …, 2017 - academic.oup.com
The importance of metabolic syndrome (MetS) lies in its associated risk of cardiovascular
disease and type 2 diabetes, as well as other harmful conditions such as nonalcoholic fatty …

[HTML][HTML] Time-restricted feeding is a preventative and therapeutic intervention against diverse nutritional challenges

A Chaix, A Zarrinpar, P Miu, S Panda - Cell metabolism, 2014 - cell.com
Because current therapeutics for obesity are limited and only offer modest improvements,
novel interventions are needed. Preventing obesity with time-restricted feeding (TRF; 8–9 hr …

[HTML][HTML] Time for food: the intimate interplay between nutrition, metabolism, and the circadian clock

G Asher, P Sassone-Corsi - Cell, 2015 - cell.com
The circadian clock, a highly specialized, hierarchical network of biological pacemakers,
directs and maintains proper rhythms in endocrine and metabolic pathways required for …