Oxidative stress and mitochondrial dysfunction in aluminium neurotoxicity and its amelioration: a review
V Kumar, KD Gill - Neurotoxicology, 2014 - Elsevier
Aluminium is light weight and toxic metal present ubiquitously on earth which has gained
considerable attention due to its neurotoxic effects. The widespread use of products made …
considerable attention due to its neurotoxic effects. The widespread use of products made …
Review of the multiple aspects of neurofilament functions, and their possible contribution to neurodegeneration
R Perrot, R Berges, A Bocquet, J Eyer - Molecular neurobiology, 2008 - Springer
Neurofilaments (NF) are the most abundant cytoskeletal component of large myelinated
axons from adult central and peripheral nervous system. Here, we provide an overview of …
axons from adult central and peripheral nervous system. Here, we provide an overview of …
[PDF][PDF] Toxic effects of metals
RA Goyer, TW Clarkson - Casarett and Doull's toxicology: the …, 1996 - biologicaldiversity.org
Metals differ from other toxic substances in that they are neither created nor destroyed by
humans. Nevertheless, their utilization by humans influences the potential for health effects …
humans. Nevertheless, their utilization by humans influences the potential for health effects …
Local modulation of neurofilament phosphorylation, axonal caliber, and slow axonal transport by myelinating Schwann cells
Studies in Trembler and control mice demonstrated that myelinating Schwann cells exert a
profound influence on axons. Extensive contacts between myelin and axons have been …
profound influence on axons. Extensive contacts between myelin and axons have been …
Aluminum and Alzheimer's disease: model studies
GD Fasman - Coordination chemistry reviews, 1996 - Elsevier
Model tangles, 13 amino acid sequences and 17 amino acid sequences (NF-M13, NF-M17)
have been synthesized and phosphorylated. Circular dichroism studies of their interaction …
have been synthesized and phosphorylated. Circular dichroism studies of their interaction …
Phosphorylation of neurofilaments is altered in amyotrophic lateral sclerosis
V Manetto, NH Sternberger, G Perry… - … of Neuropathology & …, 1988 - academic.oup.com
We used a library of monoclonal antibodies (Mab) that distinguish phosphorylated (P+) and
non-phosphorylated (P−) neurofilament (NF) epitopes to examine phosphorylation of NF in …
non-phosphorylated (P−) neurofilament (NF) epitopes to examine phosphorylation of NF in …
Anti-GQ1b ganglioside antibodies mediate complement-dependent destruction of the motor nerve terminal
GM O'Hanlon, JJ Plomp, M Chakrabarti, I Morrison… - Brain, 2001 - academic.oup.com
Miller–Fisher syndrome is an autoimmune neuropathy characterized by ataxia, areflexia and
ophthalmoplegia, and in the majority of cases the presence of high titres of anti-GQ1b …
ophthalmoplegia, and in the majority of cases the presence of high titres of anti-GQ1b …
Inorganics and hormesis
EJ Calabrese, LA Baldwin - Critical reviews in toxicology, 2003 - Taylor & Francis
The article is a comprehensive review of the occurrence of hormetic dose-response
relationships induced by inorganic agents, including toxic agents, of significant …
relationships induced by inorganic agents, including toxic agents, of significant …
Ligand specific effects on aluminum incorporation and toxicity in neurons and astrocytes
L Lévesque, CA Mizzen, DR McLachlan, PE Fraser - Brain research, 2000 - Elsevier
Aluminum is present in many manufactured foods and medicines and is added to drinking
water for purification purposes. It has been proposed that aluminum is a contributing factors …
water for purification purposes. It has been proposed that aluminum is a contributing factors …
Neuronal intermediate filaments and neurodegenerative disorders
R Perrot, J Eyer - Brain research bulletin, 2009 - Elsevier
Intermediate filaments represent the most abundant cytoskeletal element in mature neurons.
Mutations and/or accumulations of neuronal intermediate filament proteins are frequently …
Mutations and/or accumulations of neuronal intermediate filament proteins are frequently …