The ability to design nanostructures with arbitrary shapes and controllable motions has
made DNA nanomaterials used widely to construct diverse nanomachines with various …

This review aims at juxtaposing common versus distinct structural and functional strategies
that are applied by aptamers, riboswitches, and ribozymes/DNAzymes. Focusing on recently …

Therapeutic DNAzymes have unceasingly intrigued the scientific community owing to their
prosperous gene regulation capability. The efficacy of DNAzymes against many types of …

Darwin's assertion that “it is mere rubbish thinking, at present, of origin of life” is no longer
valid. By synthesizing origin of life (OoL) research from its inception to recent findings, with a …

As biomolecules essential for sustaining life, proteins are generated from long chains of 20
different α‐amino acids that are folded into unique 3D structures. In particular, many proteins …

DNA strands with unique secondary structures can catalyze various chemical reactions and
mimic natural enzymes with the assistance of cofactors, which have attracted much research …

DNAzymes are catalytically active single-stranded DNAs in which DNAzyme 10–23 (Dz 10–
23) consists of a catalytic core and a substrate-binding arm that reduces gene expression …

Understanding the molecular features of catalytically active DNA sequences, so‐called
DNAzymes, is essential not only for our understanding of the fundamental properties of …

We combine molecular dynamics, statistical mechanics, and hybrid quantum
mechanics/molecular mechanics simulations to describe mechanistically the severe acute …

Oligonucleotides are advancing as essential materials for the development of new
therapeutics, artificial genes, or in storage of information applications. Hitherto, our capacity …