[HTML][HTML] The cancer microenvironment: mechanical challenges of the metastatic cascade

SE Amos, YS Choi - Frontiers in Bioengineering and Biotechnology, 2021 - frontiersin.org
The metastatic cascade presents a significant challenge to patient survival in the fight
against cancer. As metastatic cells disseminate and colonize a secondary site, stepwise …

[HTML][HTML] Microfluidic lab-on-a-chip for studies of cell migration under spatial confinement

F Sala, C Ficorella, R Osellame, JA Käs… - Biosensors, 2022 - mdpi.com
Understanding cell migration is a key step in unraveling many physiological phenomena
and predicting several pathologies, such as cancer metastasis. In particular, confinement …

Recent advance in cell patterning techniques: Approaches, applications and future prospects

W Yang, Z Wang, T Yu, Y Chen, Z Ge - Sensors and Actuators A …, 2022 - Elsevier
Cell patterning technology is an effective technique to understand cell behaviors by
precisely controlling the position of cells revealing the major contributions of cells in basic …

Single-cell patterning technology for biological applications

Z Wang, B Lang, Y Qu, L Li, Z Song, Z Wang - Biomicrofluidics, 2019 - pubs.aip.org
Single-cell patterning technology has revealed significant contributions of single cells to
conduct basic and applied biological studies in vitro such as the understanding of basic cell …

[HTML][HTML] Emerging trends in modeling human liver disease in vitro

GH Underhill, SR Khetani - APL bioengineering, 2019 - pubs.aip.org
The liver executes 500+ functions, such as protein synthesis, xenobiotic metabolism, bile
production, and metabolism of carbohydrates/fats/proteins. Such functions can be severely …

Injectable PEG Hydrogels with Tissue‐Like Viscoelasticity Formed through Reversible Alendronate‐Calcium Phosphate Crosslinking for Cell‐Material Interactions

H Yu, Z Yan, CA Dreiss, GG Gaitano… - Advanced …, 2024 - Wiley Online Library
Synthetic hydrogels provide controllable 3D environments, which can be used to study
fundamental biological phenomena. The growing body of evidence that cell behavior …

Directed vertical cell migration via bifunctionalized nanomaterials in 3D step-gradient nanocomposite hydrogels

A Motealleh, NS Kehr - Biomaterials Science, 2020 - pubs.rsc.org
Directional cell migration plays an important role in embryonic development, tissue
regeneration, wound healing, and proper immune responses. In order to control cell …

Research of restricted migration evaluation of MDA-MB-231 cells in 2D and 3D co-culture models

Z Du, S Yang, Q Gong, Z Lin… - … Biology and Medicine, 2023 - journals.sagepub.com
The restricted migration evaluation is conducive to more complex tumor migration research
because of the conformity with in vivo tumors. However, the differences between restricted …

A Review of Fabrication and Applications of Confined Microchannels for Cell Migration Assay

MB Mazalan, R Toyohara, T Ohashi - International Journal of Precision …, 2024 - Springer
Cell migration is an essential process in a number of physiological and pathological events,
and known to be modulated by external microenvironment because cells may sense …

Trends in confinement-induced cell migration and multi-omics analysis

J Lu, XZ Chen, Y Liu, YJ Liu, B Liu - Analytical and Bioanalytical Chemistry, 2024 - Springer
Cell migration is an essential manner of different cell lines that are involved in embryological
development, immune responses, tumorigenesis, and metastasis in vivo. Physical …