Next-generation snake venomics: protein-locus resolution through venom proteome decomplexation

JJ Calvete - Expert review of proteomics, 2014 - Taylor & Francis
Venom research has been continuously enhanced by technological advances. High-
throughput technologies are changing the classical paradigm of hypothesis-driven research …

Centipede venom: recent discoveries and current state of knowledge

EAB Undheim, BG Fry, GF King - Toxins, 2015 - mdpi.com
Centipedes are among the oldest extant venomous predators on the planet. Armed with a
pair of modified, venom-bearing limbs, they are an important group of predatory arthropods …

Domain loss enabled evolution of novel functions in the snake three-finger toxin gene superfamily

I Koludarov, T Senoner, TNW Jackson… - Nature …, 2023 - nature.com
Abstract Three-finger toxins (3FTXs) are a functionally diverse family of toxins, apparently
unique to venoms of caenophidian snakes. Although the ancestral function of 3FTXs is …

Restriction and recruitment—gene duplication and the origin and evolution of snake venom toxins

AD Hargreaves, MT Swain, MJ Hegarty… - Genome biology and …, 2014 - academic.oup.com
Snake venom has been hypothesized to have originated and diversified through a process
that involves duplication of genes encoding body proteins with subsequent recruitment of …

Intraspecific venom variation in the medically significant Southern Pacific Rattlesnake (Crotalus oreganus helleri): biodiscovery, clinical and evolutionary implications

K Sunagar, EAB Undheim, H Scheib, ECK Gren… - Journal of …, 2014 - Elsevier
Due to the extreme variation of venom, which consequently results in drastically variable
degrees of neutralization by CroFab antivenom, the management and treatment of …

Three-fingered RAVERs: Rapid Accumulation of Variations in Exposed Residues of snake venom toxins

K Sunagar, TNW Jackson, EAB Undheim, SA Ali… - Toxins, 2013 - mdpi.com
Three-finger toxins (3FTx) represent one of the most abundantly secreted and potently toxic
components of colubrid (Colubridae), elapid (Elapidae) and psammophid (Psammophiinae …

Dynamic genetic differentiation drives the widespread structural and functional convergent evolution of snake venom proteinaceous toxins

B Xie, D Dashevsky, D Rokyta, P Ghezellou, B Fathinia… - BMC biology, 2022 - Springer
Background The explosive radiation and diversification of the advanced snakes (superfamily
Colubroidea) was associated with changes in all aspects of the shared venom system …

Snake venom in context: neglected clades and concepts

TNW Jackson, H Jouanne, N Vidal - Frontiers in Ecology and …, 2019 - frontiersin.org
Despite the fact that venom is an intrinsically ecological trait, the ecological perspective has
been widely neglected in toxinological research. This neglect has hindered our …

Expression of venom gene homologs in diverse python tissues suggests a new model for the evolution of snake venom

J Reyes-Velasco, DC Card, AL Andrew… - Molecular biology …, 2015 - academic.oup.com
Snake venom gene evolution has been studied intensively over the past several decades,
yet most previous studies have lacked the context of complete snake genomes and the full …

How the cobra got its flesh-eating venom: Cytotoxicity as a defensive innovation and its co-evolution with hooding, aposematic marking, and spitting

N Panagides, TNW Jackson, MP Ikonomopoulou… - Toxins, 2017 - mdpi.com
The cytotoxicity of the venom of 25 species of Old World elapid snake was tested and
compared with the morphological and behavioural adaptations of hooding and spitting. We …