The enantioselective synthesis of spirocycles has long been pursued by organic chemists.
Despite their unique 3D properties and presence in several natural products, the difficulty in …

Chiral spirooxindoles are privileged heterocyclic motifs, which are widely found in natural
alkaloids and pharmaceuticals. Moreover, the construction of chiral spiro-cyclic frameworks …

This review is focused on the enantioselective synthesis of 3, 4-dihydropyran derivatives,
whose importance as chiral building blocks in the synthesis of bioactive molecules and …

A new bifunctional squaramide organocatalyst derived from l-proline mediated the first
enantioselective synthesis of dihydrospiro [indoline-3, 4′-pyrano [2, 3-c] pyrazole] …

Against the backdrop of the established biological properties of 2-hydroxynaphthoquinone
(lawsone) and related compounds, the rational design of chiral β-butyl lawsone derivatives …

Asymmetric reactions and the synthesis of various quinones, carried out in the presence of
chiral organocatalysts and metal–ligand complexes, are reviewed here. The role of …

This digest summarizes the recent progress made in the organocatalytic asymmetric
reactions involving 1, 4-quinone derivatives. The roles of quinones as Michael donors …

A remote cascade asymmetric inverse‐electron‐demand oxa‐Diels‐Alder reaction of allyl
ketones with isatin‐derived β, γ‐unsaturated α‐keto esters has been developed in the …

The asymmetric formation of spiroindenes containing up to four contiguous stereocenters
from the reaction of benzofulvenes with 2, 4‐dienals through trienamine catalysis is …

Summary β, γ-Unsaturated α-ketoesters prove to be versatile organic synthons participating
in diverse catalytic asymmetric transformations with the breathtaking development of organo …