Preclinical murine models to study lung infection with Mycobacterium abscessus complex
F Nicola, DM Cirillo, NI Lorè - Tuberculosis, 2023 - Elsevier
Mycobacterium abscessus is a non-tuberculous mycobacterium (NTM) able to cause
invasive pulmonary infections, named NTM pulmonary disease. The therapeutic approaches …
invasive pulmonary infections, named NTM pulmonary disease. The therapeutic approaches …
Animal models of cystic fibrosis in the era of highly effective modulator therapies
BR Grubb, A Livraghi-Butrico - Current opinion in pharmacology, 2022 - Elsevier
Few human genetic diseases can rely on the availability of as many and as diverse animal
models as cystic fibrosis (CF), a multiorgan syndrome caused by functional absence of cystic …
models as cystic fibrosis (CF), a multiorgan syndrome caused by functional absence of cystic …
Rough and smooth variants of Mycobacterium abscessus are differentially controlled by host immunity during chronic infection of adult zebrafish
JY Kam, E Hortle, E Krogman, SE Warner… - Nature …, 2022 - nature.com
Prevalence of Mycobacterium abscessus infections is increasing in patients with respiratory
comorbidities. After initial colonisation, M. abscessus smooth colony (S) variants can …
comorbidities. After initial colonisation, M. abscessus smooth colony (S) variants can …
Combined host-and pathogen-directed therapy for the control of Mycobacterium abscessus infection
N Poerio, C Riva, T Olimpieri, M Rossi… - Microbiology …, 2022 - Am Soc Microbiol
Mycobacterium abscessus is the etiological agent of severe pulmonary infections in
vulnerable patients, such as those with cystic fibrosis (CF), where it represents a relevant …
vulnerable patients, such as those with cystic fibrosis (CF), where it represents a relevant …
A rabbit model to study antibiotic penetration at the site of infection for nontuberculous mycobacterial lung disease: macrolide case study
Nontuberculous mycobacterial pulmonary disease (NTM-PD) is a potentially fatal infectious
disease requiring long treatment duration with multiple antibiotics and against which there is …
disease requiring long treatment duration with multiple antibiotics and against which there is …
Biotin-dependent cell envelope remodelling is required for Mycobacterium abscessus survival in lung infection
MR Sullivan, K McGowen, Q Liu, C Akusobi… - Nature …, 2023 - nature.com
Mycobacterium abscessus is an emerging pathogen causing lung infection predominantly in
patients with underlying structural abnormalities or lung disease and is resistant to most …
patients with underlying structural abnormalities or lung disease and is resistant to most …
Antimicrobial susceptibility of Mycobacterium abscessus and treatment of pulmonary and extra-pulmonary infections
S Tunesi, A Zelazny, Z Awad, F Mougari, J Buyck… - Clinical Microbiology …, 2023 - Elsevier
Background Mycobacterium abscessus (MAB) is the mycobacterial species the least
susceptible to antimicrobials. Infections are difficult to treat and cure rates are below 50 …
susceptible to antimicrobials. Infections are difficult to treat and cure rates are below 50 …
The small non-coding RNA B11 regulates multiple facets of Mycobacterium abscessus virulence
M Bar-Oz, MC Martini, MN Alonso, M Meir… - Plos …, 2023 - journals.plos.org
Mycobacterium abscessus causes severe disease in patients with cystic fibrosis. Little is
known in M. abscessus about the roles of small regulatory RNAs (sRNA) in gene regulation …
known in M. abscessus about the roles of small regulatory RNAs (sRNA) in gene regulation …
Preclinical murine models for the testing of antimicrobials against Mycobacterium abscessus pulmonary infections: Current practices and recommendations
Mycobacterium abscessus, a rapidly growing nontuberculous mycobacterium, is
increasingly recognized as an important pathogen of the human lung, disproportionally …
increasingly recognized as an important pathogen of the human lung, disproportionally …
Evaluation of Anti-Mycobacterial Compounds in a Silkworm Infection Model with Mycobacteroides abscessus
K Hosoda, N Koyama, H Hamamoto, A Yagi, R Uchida… - Molecules, 2020 - mdpi.com
Among four mycobacteria, Mycobacterium avium, M. intracellulare, M. bovis BCG and
Mycobacteroides (My.) abscessus, we established a silkworm infection assay with My …
Mycobacteroides (My.) abscessus, we established a silkworm infection assay with My …