Alkaptonuria

G Bernardini, D Braconi, A Zatkova, N Sireau… - Nature Reviews …, 2024 - nature.com
Alkaptonuria is a rare inborn error of metabolism caused by the deficiency of homogentisate
1, 2-dioxygenase activity. The consequent homogentisic acid (HGA) accumulation in body …

Alkaptonuria: From Molecular Insights to a Dedicated Digital Platform

MS Milella, M Geminiani, A Trezza, A Visibelli… - Cells, 2024 - mdpi.com
Alkaptonuria (AKU) is a genetic disorder that affects connective tissues of several body
compartments causing cartilage degeneration, tendon calcification, heart problems, and an …

Phenolic polymers as model melanins

HA Galeb, J Eichhorn, S Harley… - Macromolecular …, 2023 - Wiley Online Library
Melanins are a class of conjugated biopolymers with varying compositions and functions,
which have a variety of potential medical and technical applications. Here, this work …

New aspects characterizing non-obese NAFLD by the analysis of the intestinal flora and metabolites using a mouse model

W Zhang, W Cheng, JH Li, Z Huang, H Lin, W Zhang - Msystems, 2024 - Am Soc Microbiol
Non-alcoholic fatty liver disease (NAFLD) is a major public health problem due to the high
incidence affecting approximately one-third of the world's population. NAFLD is usually …

Genomic Insights into Moderately Thermophilic Methanotrophs of the Genus Methylocaldum

NA Delherbe, D Pearce, SY But, JC Murrell… - Microorganisms, 2024 - mdpi.com
Considering the increasing interest in understanding the biotic component of methane
removal from our atmosphere, it becomes essential to study the physiological characteristics …