Early life exposure to per-and polyfluoroalkyl substances (PFAS) and latent health outcomes: A review including the placenta as a target tissue and possible driver of …

BE Blake, SE Fenton - Toxicology, 2020 - Elsevier
Per-and polyfluoroalkyl substances (PFAS) are ubiquitous drinking water contaminants of
concern due to mounting evidence implicating adverse health outcomes associated with …

Thyroid effects of endocrine disrupting chemicals

M Boas, U Feldt-Rasmussen, KM Main - Molecular and cellular …, 2012 - Elsevier
In recent years, many studies of thyroid-disrupting effects of environmental chemicals have
been published. Of special concern is the exposure of pregnant women and infants, as …

Risk to human health related to the presence of perfluoroalkyl substances in food

EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2020 - Wiley Online Library
Abstract The European Commission asked EFSA for a scientific evaluation on the risks to
human health related to the presence of perfluoroalkyl substances (PFAS s) in food. Based …

Perfluoroalkyl acids: a review of monitoring and toxicological findings

C Lau, K Anitole, C Hodes, D Lai… - Toxicological …, 2007 - academic.oup.com
In recent years, human and wildlife monitoring studies have identified perfluoroalkyl acids
(PFAA) worldwide. This has led to efforts to better understand the hazards that may be …

Epidemiologic evidence on the health effects of perfluorooctanoic acid (PFOA)

K Steenland, T Fletcher, DA Savitz - Environmental health …, 2010 - ehp.niehs.nih.gov
Objective and sources We reviewed the epidemiologic literature for PFOA. Data synthesis
Perfluorooctanoic acid (PFOA) does not occur naturally but is present in the serum of most …

[HTML][HTML] Exposure to perfluoroalkyl substances and thyroid function in pregnant women and children: a systematic review of epidemiologic studies

V Ballesteros, O Costa, C Iniguez, T Fletcher… - Environment …, 2017 - Elsevier
Abstract Introduction Thyroid hormones (THs) are especially important for brain maturation
and development during the fetal period and childhood. Several epidemiological studies …

Thyroid-disrupting chemicals and brain development: an update

BB Mughal, JB Fini, BA Demeneix - Endocrine connections, 2018 - ec.bioscientifica.com
This review covers recent findings on the main categories of thyroid hormone–disrupting
chemicals and their effects on brain development. We draw mostly on epidemiological and …

Serum biomarkers of exposure to perfluoroalkyl substances in relation to serum testosterone and measures of thyroid function among adults and adolescents from …

RC Lewis, LE Johns, JD Meeker - International journal of environmental …, 2015 - mdpi.com
Perfluoroalkyl substances (PFASs) are a group of environmentally-persistent chemicals that
have been widely used in many industrial applications. There is human and animal …

Thyroid function and perfluoroalkyl acids in children living near a chemical plant

MJ Lopez-Espinosa, D Mondal… - Environmental …, 2012 - ehp.niehs.nih.gov
Background: Animal studies suggest that some perfluoroalkyl acids (PFAAs), including
perfluorooctanoate (PFOA), perfluorooctane sulfonate (PFOS), and perfluorononanoic acid …

Structure-based investigation on the interaction of perfluorinated compounds with human liver fatty acid binding protein

L Zhang, XM Ren, LH Guo - Environmental science & technology, 2013 - ACS Publications
Perfluorinated compounds (PFCs) are known to accumulate in liver and induce
hepatotoxicity on experimental animals. Liver fatty acid binding protein (L-FABP) is …