Modern diagnosis of GERD: the Lyon Consensus

CP Gyawali, PJ Kahrilas, E Savarino, F Zerbib, F Mion… - Gut, 2018 - gut.bmj.com
Clinical history, questionnaire data and response to antisecretory therapy are insufficient to
make a conclusive diagnosis of GERD in isolation, but are of value in determining need for …

Ambulatory reflux monitoring for diagnosis of gastro‐esophageal reflux disease: update of the Porto consensus and recommendations from an international …

S Roman, CP Gyawali, E Savarino… - …, 2017 - Wiley Online Library
Background An international group of experts evaluated and revised recommendations for
ambulatory reflux monitoring for the diagnosis of gastro‐esophageal reflux disease (GERD) …

ACG clinical guidelines: clinical use of esophageal physiologic testing

CP Gyawali, DA Carlson, JW Chen… - Official journal of the …, 2020 - journals.lww.com
Esophageal symptoms are common and may indicate the presence of gastroesophageal
reflux disease (GERD), structural processes, motor dysfunction, behavioral conditions, or …

[HTML][HTML] Advances in the physiological assessment and diagnosis of GERD

E Savarino, AJ Bredenoord, M Fox… - Nature reviews …, 2017 - nature.com
GERD is a common condition worldwide. Key mechanisms of disease include abnormal
oesophagogastric junction structure and function, and impaired oesophageal clearance. A …

Postreflux swallow‐induced peristaltic wave index and nocturnal baseline impedance can link PPI‐responsive heartburn to reflux better than acid exposure time

L Frazzoni, M Frazzoni, N de Bortoli… - …, 2017 - Wiley Online Library
Background Acid exposure time (AET) is considered the most useful parameter to predict
response of reflux‐related heartburn to medical or surgical treatment. However, recent …

Novel impedance‐pH parameters are associated with proton pump inhibitor response in patients with inconclusive diagnosis of gastro‐oesophageal reflux disease …

M Ribolsi, M Frazzoni, E Marabotto… - Alimentary …, 2021 - Wiley Online Library
Summary Background The Lyon Consensus delineates impedance‐pH parameters that can
demonstrate/exclude gastro‐oesophageal reflux disease (GERD). In patients with acid …

Mean nocturnal baseline impedance correlates with symptom outcome when acid exposure time is inconclusive on esophageal reflux monitoring

A Rengarajan, E Savarino, M Della Coletta… - Clinical …, 2020 - Elsevier
Background & Aims Abnormal acid exposure time (AET) is associated with good outcomes
of symptoms from antireflux therapy. Low esophageal mean nocturnal baseline impedance …

Development and validation of a mucosal impedance contour analysis system to distinguish esophageal disorders

DA Patel, T Higginbotham, JC Slaughter, M Aslam… - Gastroenterology, 2019 - Elsevier
Background & Aims Diagnostic testing for chronic esophageal disorders relies on
histopathology analysis of biopsies or uncomfortable transnasal catheters or wireless pH …

Impedance-pH monitoring for diagnosis of reflux disease: new perspectives

M Frazzoni, N De Bortoli, L Frazzoni, S Tolone… - Digestive diseases and …, 2017 - Springer
Heartburn is the most specific symptom of gastroesophageal reflux disease (GERD). In
clinical practice, heartburn relief by a proton pump inhibitor (PPI) trial does suffice to confirm …

[HTML][HTML] Artificial intelligence in the diagnosis of upper gastrointestinal diseases

P Visaggi, N de Bortoli, B Barberio… - Journal of Clinical …, 2022 - journals.lww.com
Artificial intelligence (AI) has enormous potential to support clinical routine workflows and
therefore is gaining increasing popularity among medical professionals. In the field of …