[HTML][HTML] The endocannabinoid system: a potential target for the treatment of various diseases

H Lowe, N Toyang, B Steele, J Bryant… - International journal of …, 2021 - mdpi.com
The Endocannabinoid System (ECS) is primarily responsible for maintaining homeostasis, a
balance in internal environment (temperature, mood, and immune system) and energy input …

Cannabidiol adverse effects and toxicity

MA Huestis, R Solimini, S Pichini… - Current …, 2019 - ingentaconnect.com
Background: Currently, there is a great interest in the potential medical use of cannabidiol
(CBD), a non-intoxicating cannabinoid. Productive pharmacological research on CBD …

Adverse effects of cannabidiol: a systematic review and meta-analysis of randomized clinical trials

E Chesney, D Oliver, A Green, S Sovi… - …, 2020 - nature.com
Cannabidiol (CBD) is being investigated as a treatment for several medical disorders but
there is uncertainty about its safety. We conducted the first systematic review and meta …

[HTML][HTML] Small molecules in the treatment of COVID-19

S Lei, X Chen, J Wu, X Duan, K Men - Signal Transduction and Targeted …, 2022 - nature.com
The outbreak of COVID-19 has become a global crisis, and brought severe disruptions to
societies and economies. Until now, effective therapeutics against COVID-19 are in high …

Trends in use, pharmacology, and clinical applications of emerging herbal nutraceuticals

EM Williamson, X Liu, AA Izzo - British Journal of …, 2020 - Wiley Online Library
The nutraceuticals market is vast, encompassing many different products with inconsistent
levels of evidence available to support their use. This overview represents a Western …

Balancing risks and benefits of cannabis use: umbrella review of meta-analyses of randomised controlled trials and observational studies

M Solmi, M De Toffol, JY Kim, MJ Choi, B Stubbs… - bmj, 2023 - bmj.com
Objective To systematically assess credibility and certainty of associations between
cannabis, cannabinoids, and cannabis based medicines and human health, from …

[HTML][HTML] Psychobehavioural and cognitive adverse events of anti-seizure medications for the treatment of developmental and epileptic encephalopathies

A Strzelczyk, S Schubert-Bast - CNS drugs, 2022 - Springer
The developmental and epileptic encephalopathies encompass a group of rare syndromes
characterised by severe drug-resistant epilepsy with onset in childhood and significant …

[HTML][HTML] Consensus recommendations on dosing and administration of medical cannabis to treat chronic pain: results of a modified Delphi process

A Bhaskar, A Bell, M Boivin, W Briques… - Journal of cannabis …, 2021 - Springer
Background Globally, medical cannabis legalization has increased in recent years and
medical cannabis is commonly used to treat chronic pain. However, there are few …

Use of cannabidiol (CBD) for the treatment of chronic pain

I Urits, K Gress, K Charipova, K Habib, D Lee… - Best Practice & …, 2020 - Elsevier
Chronic pain can be recurrent or constant pain that lasts for longer than 3 months and can
result in disability, suffering, and a physical disturbance. Related to the complex nature of …

[HTML][HTML] Therapeutic and clinical foundations of cannabidiol therapy for difficult-to-treat seizures in children and adults with refractory epilepsies

DS Reddy - Experimental neurology, 2023 - Elsevier
Novel and effective antiseizure medications are needed to treat refractory and rare forms of
epilepsy. Cannabinoids, which are obtained from the cannabis plant, have a long history of …