Tutorial: Analysis of motor unit discharge characteristics from high-density surface EMG signals

A Del Vecchio, A Holobar, D Falla, F Felici… - Journal of …, 2020 - Elsevier
Recent work demonstrated that it is possible to identify motor unit discharge times from high-
density surface EMG (HDEMG) decomposition. Since then, the number of studies that use …

Sex differences in motor unit behaviour: A review

T Lulic-Kuryllo, JG Inglis - Journal of Electromyography and Kinesiology, 2022 - Elsevier
The lack of systematic investigations on sex-related differences in motor unit behaviour
poses a challenge in understanding and optimizing health and performance in males and …

Estimates of persistent inward currents in lower limb motoneurons are larger in females than in males

ST Jenz, JA Beauchamp, MM Gomes… - Journal of …, 2023 - journals.physiology.org
Noninvasive recordings of motor unit (MU) spike trains help us understand how the nervous
system controls movement and how it adapts to various physiological conditions. The …

Estimates of persistent inward currents are reduced in upper limb motor units of older adults

AS Hassan, ME Fajardo, M Cummings… - The Journal of …, 2021 - Wiley Online Library
Ageing is a natural process causing alterations in the neuromuscular system, which
contributes to reduced quality of life. Motor unit (MU) contributes to weakness, but the …

Blockade of 5‐HT2 receptors suppresses motor unit firing and estimates of persistent inward currents during voluntary muscle contraction in humans

BI Goodlich, A Del Vecchio, SA Horan… - The Journal of …, 2023 - Wiley Online Library
Serotonergic neuromodulation contributes to enhanced voluntary muscle activation.
However, it is not known how the likely motoneurone receptor candidate (5‐HT2) influences …

Facilitation–inhibition control of motor neuronal persistent inward currents in young and older adults

LBR Orssatto, GL Fernandes… - The Journal of …, 2022 - Wiley Online Library
A well‐coordinated facilitation–inhibition control of motor neuronal persistent inward
currents (PICs) via diffuse neuromodulation and local inhibition is essential to ensure motor …

Sex differences in the detection of motor unit action potentials identified using high-density surface electromyography

CA Taylor, BH Kopicko, F Negro… - … of Electromyography and …, 2022 - Elsevier
Sex-related disparities in force production of humans have been widely observed. Previous
literature has attributed differences in peripheral traits, such as muscle size, to explain these …

Effects of reciprocal inhibition and whole‐body relaxation on persistent inward currents estimated by two different methods

RNO Mesquita, JL Taylor, GS Trajano… - The Journal of …, 2022 - Wiley Online Library
Persistent inward currents (PICs) are crucial for initiation, acceleration, and maintenance of
motoneuron firing. As PICs are highly sensitive to synaptic inhibition and facilitated by …

A geometric approach to quantifying the neuromodulatory effects of persistent inward currents on individual motor unit discharge patterns

JA Beauchamp, GEP Pearcey… - Journal of neural …, 2023 - iopscience.iop.org
Objective. All motor commands flow through motoneurons, which entrain control of their
innervated muscle fibers, forming a motor unit (MU). Owing to the high fidelity of action …

[HTML][HTML] Estimation of self-sustained activity produced by persistent inward currents using firing rate profiles of multiple motor units in humans

B Afsharipour, N Manzur… - Journal of …, 2020 - journals.physiology.org
Persistent inward calcium and sodium currents (IP) activated during motoneuron recruitment
help synaptic inputs maintain self-sustained firing until derecruitment. Here, we estimate the …