Emerging trends in the novel drug delivery approaches for the treatment of lung cancer

P Sharma, M Mehta, DS Dhanjal, S Kaur… - Chemico-biological …, 2019 - Elsevier
Cancer is one of the major diseases that cause a high number of deaths globally. Of the
major types of cancers, lung cancer is known to be the most chronic form of cancer in the …

Nanoscale self-assembly for therapeutic delivery

S Yadav, AK Sharma, P Kumar - Frontiers in Bioengineering and …, 2020 - frontiersin.org
Self-assembly is the process of association of individual units of a material into highly
arranged/ordered structures/patterns. It imparts unique properties to both inorganic and …

[HTML][HTML] Nano-based drug delivery systems: Conventional drug delivery routes, recent developments and future prospects

A Sultana, M Zare, V Thomas, TSS Kumar… - Medicine in Drug …, 2022 - Elsevier
Drug delivery can be defined as the group of approaches a drug or pharmacologically active
agent can be transported to the target cell to treat disease or health issue. Conventional …

Poly (propylene imine) dendrimer as an emerging polymeric nanocarrier for anticancer drug and gene delivery

V Singh, A Sahebkar, P Kesharwani - European Polymer Journal, 2021 - Elsevier
Dendrimers are well-defined globular macromolecules with multiple polymeric branching
that are amenable to undergo structural modifications. This property makes dendrimers …

Dendrimers as nanoscale vectors: Unlocking the bars of cancer therapy

AD Dey, A Bigham, Y Esmaeili, M Ashrafizadeh… - Seminars in Cancer …, 2022 - Elsevier
Chemotherapy is the first choice in the treatment of cancer and is always preferred to other
approaches such as radiation and surgery, but it has never met the need of patients for a …

A new era in posterior segment ocular drug delivery: Translation of systemic, cell-targeted, dendrimer-based therapies

RM Kannan, I Pitha, KS Parikh - Advanced Drug Delivery Reviews, 2023 - Elsevier
Vision impairment and loss due to posterior segment ocular disorders, including age-related
macular degeneration and diabetic retinopathy, are a rapidly growing cause of disability …

Editorial focus: understanding off-target effects as the key to successful RNAi therapy

R Bartoszewski, AF Sikorski - Cellular & molecular biology letters, 2019 - Springer
With the first RNA interference (RNAi) drug (ONPATTRO (patisiran)) on the market, we
witness the RNAi therapy field reaching a critical turning point, when further improvements in …

Dendrimer nanoparticles for colorectal cancer applications

MR Carvalho, RL Reis, JM Oliveira - Journal of Materials Chemistry B, 2020 - pubs.rsc.org
Cancer nanotechnology is a prolific field of research, where nanotools are employed to
diagnose and treat cancer with unprecedented precision. Targeted drug delivery is …

Research and development of drug delivery systems based on drug transporter and nano-formulation

Y Peng, L Chen, S Ye, Y Kang, J Liu, S Zeng… - Asian journal of …, 2020 - Elsevier
In recent years, the continuous occurrence of multi-drug resistance in the clinic has made
people pay more attention to the transporter. Changes in the expression and activity of …

[HTML][HTML] Liposomal delivery of CRISPR/Cas9

S Zhen, X Li - Cancer gene therapy, 2020 - nature.com
Liposomes are one of the most widely investigated carriers for CRISPR/Cas9 delivery. The
surface properties of liposomal carriers, including the surface charge, PEGylation, and …