Potential impact of microRNA gene polymorphisms in the pathogenesis of diabetes and atherosclerotic cardiovascular disease

I Elfaki, R Mir, MM Mir, FM AbuDuhier… - Journal of personalized …, 2019 - mdpi.com
MicroRNAs (miRNAs) are endogenous, small (18–23 nucleotides), non-coding RNA
molecules. They regulate the posttranscriptional expression of their target genes. MiRNAs …

Network pharmacology and metabolomics study on the intervention of traditional Chinese medicine Huanglian Decoction in rats with type 2 diabetes mellitus

L Pan, Z Li, Y Wang, B Zhang, G Liu, J Liu - Journal of ethnopharmacology, 2020 - Elsevier
Ethnopharmacological relevance Type 2 diabetes mellitus (T2DM) is currently one of the
most prominent and global chronic conditions. Huanglian Decoction (HLD) is a traditional …

[HTML][HTML] Research on Traditional Chinese Medicine Syndrome Animal Models and Multi-omics Biomarkers in Type II Diabetes: A Review

Y Wang, Y Gao, B Zhao - Pharmacological Research-Modern Chinese …, 2024 - Elsevier
Introduction Diabetes, a chronic metabolic disease marked by hyperglycemia,
predominantly manifests as Type 2 Diabetes Mellitus (T2DM), representing over 90% of …

Identification of candidate biomarkers and pathways associated with type 1 diabetes mellitus using bioinformatics analysis

M Pujar, B Vastrad, S Kavatagimath, C Vastrad… - Scientific Reports, 2022 - nature.com
Type 1 diabetes mellitus (T1DM) is a metabolic disorder for which the underlying molecular
mechanisms remain largely unclear. This investigation aimed to elucidate essential …

Chronic heavy alcohol consumption influences the association between genetic variants of GCK or INSR and the development of diabetes in men: A 12-year follow …

HB Jang, MJ Go, SI Park, HJ Lee, SB Cho - Scientific Reports, 2019 - nature.com
Chronic heavy alcohol consumption is a risk factor for diabetes, which is characterized by
impaired β-cell function and insulin resistance. We aimed to determine whether the …

The miRNA variants MIR196A2 (rs11614913) and MIR423 (rs6505162) contribute to an increase in the risk of myocardial infarction

M Uzair, TU Haq, S Ali, M Hussain… - … Genetics & Genomic …, 2024 - Wiley Online Library
Introduction MicroRNAs (miRNAs) are small, single‐stranded RNA molecules that
negatively regulate gene expression and play a key role in the pathogenesis of human …

Identification of candidate biomarkers and pathways associated with type 1 diabetes mellitus using bioinformatics analysis

B Vastrad, C Vastrad - bioRxiv, 2021 - biorxiv.org
Type 1 diabetes mellitus (T1DM) is a metabolic disorder for which the underlying molecular
mechanisms remain largely unclear. This investigation aimed to elucidate essential …

[PDF][PDF] Polymorphism of human insulin receptor INSR gene rs1366600 in Iraqi patients with type2 diabetes mellitus

MH Foad, IH Ahmed - researchgate.net
The aim of this study was to investigate the association of polymorphisms of human insulin
receptor gene INSR rs1366600 to the susceptibility of type2 diabetes mellitus in diabetic …