[HTML][HTML] Genetic pathways of aging and their relevance in the dog as a natural model of human aging
Aging research has experienced a burst of scientific efforts in the last decades as the
growing ratio of elderly people has begun to pose an increased burden on the healthcare …
growing ratio of elderly people has begun to pose an increased burden on the healthcare …
[HTML][HTML] Canine mammary carcinomas: a comparative analysis of altered gene expression
FM Lutful Kabir, CE Alvarez, RC Bird - Veterinary Sciences, 2015 - mdpi.com
Breast cancer represents the second most frequent neoplasm in humans and sexually intact
female dogs after lung and skin cancers, respectively. Many similar features in human and …
female dogs after lung and skin cancers, respectively. Many similar features in human and …
Statins downregulate YAP and TAZ and exert anti‐cancer effects in canine mammary tumour cells
AL Vigneau, C Rico, D Boerboom… - Veterinary and …, 2022 - Wiley Online Library
Canine mammary tumours (CMTs) are the most common neoplasms in intact bitches, and
few chemotherapeutic options are available for highly invasive and metastatic tumours …
few chemotherapeutic options are available for highly invasive and metastatic tumours …
Altered microRNA expression profiles and regulation of INK4A/CDKN2A tumor suppressor genes in canine breast cancer models
FM Lutful Kabir, P DeInnocentes… - Journal of Cellular …, 2015 - Wiley Online Library
ABSTRACT microRNA (miRNA) expression profiling of cancer versus normal cells may
reveal the characteristic regulatory features that can be correlated to altered gene …
reveal the characteristic regulatory features that can be correlated to altered gene …
[HTML][HTML] Estrogen receptor-α, progesterone receptor, and c-erbB/HER-family receptor mRNA detection and phenotype analysis in spontaneous canine models of …
Well characterized, stable, p16-defective canine mammary cancer (CMT) cell lines and
normal canine mammary epithelial cells were used to investigate expression of the major …
normal canine mammary epithelial cells were used to investigate expression of the major …
[HTML][HTML] Promoter methylation of p16 and RASSF1A genes may contribute to the risk of papillary thyroid cancer: A meta-analysis
JL Jiang, GL Tian, SJ Chen… - Experimental and …, 2015 - spandidos-publications.com
The aim of the present meta-analysis was to investigate the correlation of promoter
methylation of the p16 and Ras association domain family 1 isoform A (RASSF1A) genes …
methylation of the p16 and Ras association domain family 1 isoform A (RASSF1A) genes …
In vitro validation of the hippo pathway as a pharmacological target for canine mammary gland tumors
S Guillemette, C Rico, P Godin, D Boerboom… - Journal of Mammary …, 2017 - Springer
Canine mammary tumors (CMTs) are the most common neoplasms in intact female dogs.
Some clinical and molecular similarities between certain CMT subtypes and breast cancer …
Some clinical and molecular similarities between certain CMT subtypes and breast cancer …
[HTML][HTML] The diagnostic significance of cerebrospinal fluid cytology and circulating tumor DNA in meningeal carcinomatosis
WY Di, YN Chen, Y Cai, Q Geng, YL Tan, CH Li… - Frontiers in …, 2023 - frontiersin.org
Objective The objective of this research is to investigate the clinical application value of
cerebrospinal fluid (CSF) cytology and circulating tumor DNA (ctDNA) in lung …
cerebrospinal fluid (CSF) cytology and circulating tumor DNA (ctDNA) in lung …
Different roles for p16INK4a‐Rb pathway and INK4a/ARF methylation between adenocarcinomas of gastric cardia and distal stomach
L Xue, Q Ouyang, J Li, X Meng, Y Li… - Journal of …, 2014 - Wiley Online Library
Abstract Background and Aim The incidence of distal gastric adenocarcinoma has
significantly decreased, but gastric cardia adenocarcinoma has been on the rise. Cardia …
significantly decreased, but gastric cardia adenocarcinoma has been on the rise. Cardia …
[PDF][PDF] 胰腺癌中Ring1B, LSD1 及P16 表达及其与预后的关系
陈辉星， 陈实， 李小燕， 陈明源， 严茂林， 黄龙 - 中国普通外科杂志, 2017 - zpwz.net
摘要目的: 探讨胰腺癌中E3 泛素连接酶亚单位Ring1B, 组蛋白赖氨酸特异性去甲基化酶1
(LSD1) 及细胞周期调节因子P16 表达与及其与患者预后的关系. 方法: 用免疫组化法检测85 …
(LSD1) 及细胞周期调节因子P16 表达与及其与患者预后的关系. 方法: 用免疫组化法检测85 …