CD36, a signaling receptor and fatty acid transporter that regulates immune cell metabolism and fate

Y Chen, J Zhang, W Cui, RL Silverstein - Journal of Experimental …, 2022 - rupress.org
CD36 is a type 2 cell surface scavenger receptor widely expressed in many immune and
non-immune cells. It functions as both a signaling receptor responding to DAMPs and …

Innate immune receptors in platelets and platelet-leukocyte interactions

PRB Dib, AC Quirino-Teixeira, LB Merij… - Journal of Leucocyte …, 2020 - academic.oup.com
Platelets are chief cells in hemostasis. Apart from their hemostatic roles, platelets are major
inflammatory effector cells that can influence both innate and adaptive immune responses …

Platelets are versatile cells: New discoveries in hemostasis, thrombosis, immune responses, tumor metastasis and beyond

XR Xu, D Zhang, BE Oswald, N Carrim… - Critical reviews in …, 2016 - Taylor & Francis
Platelets are small anucleate blood cells generated from megakaryocytes in the bone
marrow and cleared in the reticuloendothelial system. At the site of vascular injury, platelet …

Platelet interaction with innate immune cells

JB Kral, WC Schrottmaier, M Salzmann… - Transfusion Medicine …, 2016 - karger.com
Beyond their traditional role in haemostasis and thrombosis, platelets are increasingly
recognised as immune modulatory cells. Activated platelets and platelet-derived …

[HTML][HTML] Platelet in thrombo-inflammation: Unraveling new therapeutic targets

S Sharma, T Tyagi, S Antoniak - Frontiers in immunology, 2022 - frontiersin.org
In the broad range of human diseases, thrombo-inflammation appears as a clinical
manifestation. Clinically, it is well characterized in context of superficial thrombophlebitis that …

[HTML][HTML] CD36, a scavenger receptor implicated in atherosclerosis

YM Park - Experimental & molecular medicine, 2014 - nature.com
CD36 is a membrane glycoprotein that is present on various types of cells, including
monocytes, macrophages, microvascular endothelial cells, adipocytes and platelets …

[HTML][HTML] Platelet-leukocyte interplay during vascular disease

WC Schrottmaier, M Mussbacher, M Salzmann… - Atherosclerosis, 2020 - Elsevier
Vascular disease is a progressive inflammatory condition fuelled by an unhealthy lifestyle of
physical inactivity, cholesterol-rich diet, and smoking. Together with endogenous factors …

[HTML][HTML] The dual role of platelet‐innate immune cell interactions in thrombo‐inflammation

J Rayes, JH Bourne, A Brill, SP Watson - Research and practice in …, 2020 - Elsevier
Beyond their role in hemostasis and thrombosis, platelets are increasingly recognized as
key regulators of the inflammatory response under sterile and infectious conditions. Both …

Atherosclerosis–a matter of unresolved inflammation

J Viola, O Soehnlein - Seminars in immunology, 2015 - Elsevier
Atherosclerosis is commonly looked upon as a chronic inflammatory disease of the arterial
wall arising from an unbalanced lipid metabolism and a maladaptive inflammatory response …

Measuring and interpreting platelet-leukocyte aggregates

M Finsterbusch, WC Schrottmaier, JB Kral-Pointner… - Platelets, 2018 - Taylor & Francis
Platelets, besides their specialised role in haemostasis and atherothrombosis, actively
modulate innate and adaptive immune responses with crucial roles in immune surveillance …