CD36, a signaling receptor and fatty acid transporter that regulates immune cell metabolism and fate
CD36 is a type 2 cell surface scavenger receptor widely expressed in many immune and
non-immune cells. It functions as both a signaling receptor responding to DAMPs and …
non-immune cells. It functions as both a signaling receptor responding to DAMPs and …
Innate immune receptors in platelets and platelet-leukocyte interactions
PRB Dib, AC Quirino-Teixeira, LB Merij… - Journal of Leucocyte …, 2020 - academic.oup.com
Platelets are chief cells in hemostasis. Apart from their hemostatic roles, platelets are major
inflammatory effector cells that can influence both innate and adaptive immune responses …
inflammatory effector cells that can influence both innate and adaptive immune responses …
Platelets are versatile cells: New discoveries in hemostasis, thrombosis, immune responses, tumor metastasis and beyond
Platelets are small anucleate blood cells generated from megakaryocytes in the bone
marrow and cleared in the reticuloendothelial system. At the site of vascular injury, platelet …
marrow and cleared in the reticuloendothelial system. At the site of vascular injury, platelet …
Platelet interaction with innate immune cells
JB Kral, WC Schrottmaier, M Salzmann… - Transfusion Medicine …, 2016 - karger.com
Beyond their traditional role in haemostasis and thrombosis, platelets are increasingly
recognised as immune modulatory cells. Activated platelets and platelet-derived …
recognised as immune modulatory cells. Activated platelets and platelet-derived …
[HTML][HTML] Platelet in thrombo-inflammation: Unraveling new therapeutic targets
In the broad range of human diseases, thrombo-inflammation appears as a clinical
manifestation. Clinically, it is well characterized in context of superficial thrombophlebitis that …
manifestation. Clinically, it is well characterized in context of superficial thrombophlebitis that …
[HTML][HTML] CD36, a scavenger receptor implicated in atherosclerosis
YM Park - Experimental & molecular medicine, 2014 - nature.com
CD36 is a membrane glycoprotein that is present on various types of cells, including
monocytes, macrophages, microvascular endothelial cells, adipocytes and platelets …
monocytes, macrophages, microvascular endothelial cells, adipocytes and platelets …
[HTML][HTML] Platelet-leukocyte interplay during vascular disease
WC Schrottmaier, M Mussbacher, M Salzmann… - Atherosclerosis, 2020 - Elsevier
Vascular disease is a progressive inflammatory condition fuelled by an unhealthy lifestyle of
physical inactivity, cholesterol-rich diet, and smoking. Together with endogenous factors …
physical inactivity, cholesterol-rich diet, and smoking. Together with endogenous factors …
[HTML][HTML] The dual role of platelet‐innate immune cell interactions in thrombo‐inflammation
Beyond their role in hemostasis and thrombosis, platelets are increasingly recognized as
key regulators of the inflammatory response under sterile and infectious conditions. Both …
key regulators of the inflammatory response under sterile and infectious conditions. Both …
Atherosclerosis–a matter of unresolved inflammation
J Viola, O Soehnlein - Seminars in immunology, 2015 - Elsevier
Atherosclerosis is commonly looked upon as a chronic inflammatory disease of the arterial
wall arising from an unbalanced lipid metabolism and a maladaptive inflammatory response …
wall arising from an unbalanced lipid metabolism and a maladaptive inflammatory response …
Measuring and interpreting platelet-leukocyte aggregates
M Finsterbusch, WC Schrottmaier, JB Kral-Pointner… - Platelets, 2018 - Taylor & Francis
Platelets, besides their specialised role in haemostasis and atherothrombosis, actively
modulate innate and adaptive immune responses with crucial roles in immune surveillance …
modulate innate and adaptive immune responses with crucial roles in immune surveillance …