Mycobacterium tuberculosis, the leading cause of death due to infection, has a dynamic and
immunomodulatory cell envelope. The cell envelope structurally and functionally varies …

Tuberculosis (TB), caused by the intracellular pathogen Mycobacterium tuberculosis,
remains one of the leading causes of mortality across the world. There is an urgent …

Bacteria display an abundance of cellular forms and can change shape during their life
cycle. Many plausible models regarding the functional significance of cell morphology have …

Cells use both deterministic and stochastic mechanisms to generate cell-to-cell
heterogeneity, which enables the population to better withstand environmental stress. Here …

Background The exact role of neutrophils in the pathogenesis of TB is poorly understood.
Recent evidence suggests that neutrophils are not simply scavenging phagocytes in …

The genus Mycobacterium contains several slow-growing human pathogens, including
Mycobacterium tuberculosis, Mycobacterium leprae, and Mycobacterium avium …

The genus Mycobacterium is best known for its two major pathogenic species, M.
tuberculosis and M. leprae, the causative agents of two of the world's oldest diseases …

Spatial organization is a hallmark of all living systems. Even bacteria, the smallest forms of
cellular life, display defined shapes and complex internal organization, showcasing a highly …

The detection of tuberculosis currently relies upon insensitive and unspecific techniques;
newer diagnostics would ideally co-opt specific bacterial processes to provide real-time …

Mycobacteria are surrounded by a complex multilayered envelope and elongate at the
poles. The principles that organize the coordinated addition of chemically diverse cell wall …