Gallic acid and gallates in human health and disease: do mitochondria hold the key to success?
Gallic acid and gallate esters are widely used as dietary supplements or additives with
clinical significances. Over the last few decades, a large number of publications have been …
clinical significances. Over the last few decades, a large number of publications have been …
Nephroprotective plant species used in traditional Mayan Medicine for renal-associated diseases
Ethnopharmacological relevance The prevalence of kidney disease has increased rapidly in
recent years and has emerged as one of the leading causes of mortality worldwide. Natural …
recent years and has emerged as one of the leading causes of mortality worldwide. Natural …
Resveratrol reduces gentamicin-induced EMT in the kidney via inhibition of reactive oxygen species and involving TGF-β/Smad pathway
Aims Gentamicin (GEN) is one of the most valuable aminoglycoside antibiotics utilized
against life-threatening bacterial infections. Unfortunately, GEN-induced nephrotoxicity …
against life-threatening bacterial infections. Unfortunately, GEN-induced nephrotoxicity …
A Flavonoid-Rich Extract of Sambucus nigra L. Reduced Lipid Peroxidation in a Rat Experimental Model of Gentamicin Nephrotoxicity
The use of gentamicin (GM) is limited due to its nephrotoxicity mediated by oxidative stress.
This study aimed to evaluate the capacity of a flavonoid-rich extract of Sambucus nigra L …
This study aimed to evaluate the capacity of a flavonoid-rich extract of Sambucus nigra L …
Zingerone mitigates carrageenan-induced inflammation through antioxidant and anti-inflammatory activities
Inflammation is the body's response against various pathogens and has a critical role in
numerous diseases. Zingerone (Zing), a bioactive substance derived from ginger root, has a …
numerous diseases. Zingerone (Zing), a bioactive substance derived from ginger root, has a …
Targeting KEAP1/Nrf2, AKT, and PPAR-γ signals as a potential protective mechanism of diosmin against gentamicin-induced nephrotoxicity
Aim Gentamicin (GM) is an aminoglycoside antibiotic effectively used for severe/life-
threatening infections. However, the clinical application of GM is limited by nephrotoxic side …
threatening infections. However, the clinical application of GM is limited by nephrotoxic side …
Ellagic acid mitigates sodium arsenite-induced renal and hepatic toxicity in male Wistar rats
Background The aim of this study was to investigate the effect of ellagic acid (EA) on arsenic-
induced renal and hepatic toxicity in rats. Methods A total number of 35 male Wistar rats …
induced renal and hepatic toxicity in rats. Methods A total number of 35 male Wistar rats …
Zein/phospholipid composite nanoparticles for successful delivery of gallic acid into ahscs: Influence of size, surface charge, and vitamin a coupling
SAA Radwan, WH El-Maadawy, C Yousry… - International journal …, 2020 - Taylor & Francis
Purpose Zein/phospholipid composite nanoparticles (CNPs) were developed as a delivery
platform for gallic acid (GA), a polyphenolic compound with reported preclinical antifibrotic …
platform for gallic acid (GA), a polyphenolic compound with reported preclinical antifibrotic …
Crocin: a protective natural antioxidant against pulmonary fibrosis induced by bleomycin
Background Idiopathic pulmonary fibrosis (IPF) is a chronic and fibrotic lung disease of
unknown causes. Given the crucial role of oxidative stress in the progression of IPF …
unknown causes. Given the crucial role of oxidative stress in the progression of IPF …
Gallic acid ameliorates sodium arsenite-induced renal and hepatic toxicity in rats
B Gholamine, G Houshmand… - Drug and chemical …, 2021 - Taylor & Francis
Chronic exposure to toxic inorganic arsenic results in the adverse health effects including
skin lesions, cardiovascular diseases, diabetes, neurological disorders, and liver and kidney …
skin lesions, cardiovascular diseases, diabetes, neurological disorders, and liver and kidney …