Molecular and cellular mechanisms of cadmium carcinogenesis

M Waisberg, P Joseph, B Hale, D Beyersmann - Toxicology, 2003 - Elsevier
Cadmium is a heavy metal, which is widely used in industry, affecting human health through
occupational and environmental exposure. In mammals, it exerts multiple toxic effects and …

Cadmium: cellular effects, modifications of biomolecules, modulation of DNA repair and genotoxic consequences (a review)

G Bertin, D Averbeck - Biochimie, 2006 - Elsevier
Cadmium is an important toxic environmental heavy metal. Occupational and environmental
pollution with cadmium results mainly from mining, metallurgy industry and manufactures of …

Cadmium-induced pathologies: where is the oxidative balance lost (or not)?

AR Nair, O DeGheselle, K Smeets… - International journal of …, 2013 - mdpi.com
Over the years, anthropogenic factors have led to cadmium (Cd) accumulation in the
environment causing various health problems in humans. Although Cd is not a Fenton-like …

Mechanisms of cadmium carcinogenesis

P Joseph - Toxicology and applied pharmacology, 2009 - Elsevier
Cadmium (Cd), a heavy metal of considerable occupational and environmental concern, has
been classified as a human carcinogen by the International Agency for Research on Cancer …

Metal-induced oxidative stress and signal transduction

SS Leonard, GK Harris, X Shi - Free Radical Biology and Medicine, 2004 - Elsevier
Occupational and environmental exposures to metals are associated with the development
of various cancers. Although carcinogenesis caused by metals has been intensively …

Metal-induced apoptosis: mechanisms

MD Pulido, AR Parrish - Mutation Research/Fundamental and Molecular …, 2003 - Elsevier
The past decade has seen an intense focus on mechanisms of apoptosis. Many important
observations on the various signaling pathways mediating apoptotic cell death have been …

Cadmium and cardiovascular diseases: cell biology, pathophysiology, and epidemiological relevance

B Messner, D Bernhard - Biometals, 2010 - Springer
Today cardiovascular diseases (CVDs) are the killer number one world wide. In 2004 an
estimated 17.1 million people died due to CVDs and this number will further increase to an …

Comparative Effects of Dietary Methylmercury on Gene Expression in Liver, Skeletal Muscle, and Brain of the Zebrafish (Danio rerio)

P Gonzalez, Y Dominique, JC Massabuau… - … science & technology, 2005 - ACS Publications
Effects of dietary methylmercury (MeHg) on gene expression were examined in three organs
(liver, skeletal muscle, and brain) of the zebrafish (Danio rerio). Adult male fish were fed over …

Signaling by carcinogenic metals and metal-induced reactive oxygen species

GK Harris, X Shi - … Research/Fundamental and Molecular Mechanisms of …, 2003 - Elsevier
Epidemiological data indicate that exposure to metal and metalloid species, including
arsenic (III), chromium (VI), and nickel (II), increases the risk of cancer, particularly of the …

Cadmium renal toxicity via apoptotic pathways

Y Fujiwara, JY Lee, M Tokumoto… - Biological and …, 2012 - jstage.jst.go.jp
Cadmium is a nonessential heavy metal and ubiquitous potential environmental pollutant.
Although the kidney proximal tubule is an important target for cadmium, the underlying …